HCSGD entry for AGK
1. General information
| Official gene symbol | AGK |
|---|---|
| Entrez ID | 55750 |
| Gene full name | acylglycerol kinase |
| Other gene symbols | CATC5 MTDPS10 MULK |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001729 | Ceramide kinase activity | IEA | molecular_function |
| GO:0003951 | NAD+ kinase activity | IEA | molecular_function |
| GO:0004143 | Diacylglycerol kinase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0007205 | Protein kinase C-activating G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0031966 | Mitochondrial membrane | IEA | cellular_component |
| GO:0046486 | Glycerolipid metabolic process | IEA | biological_process |
| GO:0046513 | Ceramide biosynthetic process | IEA | biological_process |
| GO:0047620 | Acylglycerol kinase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9783160062 | 0.0454192660 | 0.9999902473 | 0.4003618553 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0071187111 |
| GSE13712_SHEAR | Down | -0.1505817992 |
| GSE13712_STATIC | Up | 0.0413319131 |
| GSE19018 | Down | -0.3649263172 |
| GSE19899_A1 | Down | -0.3583002560 |
| GSE19899_A2 | Up | 0.0151367007 |
| PubMed_21979375_A1 | Up | 0.3035189743 |
| PubMed_21979375_A2 | Down | -0.2244757464 |
| GSE35957 | Down | -0.3979981645 |
| GSE36640 | Down | -0.1622296034 |
| GSE54402 | Down | -0.2871456745 |
| GSE9593 | Down | -0.1041155679 |
| GSE43922 | Down | -0.1931174821 |
| GSE24585 | Up | 0.0424384504 |
| GSE37065 | Up | 0.1488979369 |
| GSE28863_A1 | Down | -0.1733767793 |
| GSE28863_A2 | Up | 0.2350858794 |
| GSE28863_A3 | Down | -0.6108370655 |
| GSE28863_A4 | Down | -0.0853489629 |
| GSE48662 | Down | -0.7755888124 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-7-5p | MIMAT0000252 | MIRT025890 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031554 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-484 | MIMAT0002174 | MIRT042001 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-378a-3p | MIMAT0000732 | MIRT043923 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
