HCSGD entry for EDEM2
1. General information
| Official gene symbol | EDEM2 |
|---|---|
| Entrez ID | 55741 |
| Gene full name | ER degradation enhancer, mannosidase alpha-like 2 |
| Other gene symbols | C20orf31 C20orf49 bA4204.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004571 | Mannosyl-oligosaccharide 1,2-alpha-mannosidase activity | IDA IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005788 | Endoplasmic reticulum lumen | IEA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006457 | Protein folding | TAS | biological_process |
| GO:0006986 | Response to unfolded protein | IEA | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0018279 | Protein N-linked glycosylation via asparagine | TAS | biological_process |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1502041108 | 0.4960691273 | 0.7748786204 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2272153409 |
| GSE13712_SHEAR | Down | -0.1406638587 |
| GSE13712_STATIC | Up | 0.0888143141 |
| GSE19018 | Up | 0.0952281494 |
| GSE19899_A1 | Down | -0.4265246818 |
| GSE19899_A2 | Down | -0.3061555578 |
| PubMed_21979375_A1 | Down | -1.1285617460 |
| PubMed_21979375_A2 | Up | 0.1438683761 |
| GSE35957 | Down | -0.3334557892 |
| GSE36640 | Up | 1.4970658174 |
| GSE54402 | Down | -0.3048961717 |
| GSE9593 | Up | 0.5304606717 |
| GSE43922 | Up | 0.0925663463 |
| GSE24585 | Up | 0.1157382777 |
| GSE37065 | Up | 0.2062633586 |
| GSE28863_A1 | Up | 0.3936928731 |
| GSE28863_A2 | Up | 0.4318277075 |
| GSE28863_A3 | Down | -0.0621029193 |
| GSE28863_A4 | Down | -0.0041181604 |
| GSE48662 | Up | 0.1016668504 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018881 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
