HCSGD entry for ARFGAP1
1. General information
| Official gene symbol | ARFGAP1 |
|---|---|
| Entrez ID | 55738 |
| Gene full name | ADP-ribosylation factor GTPase activating protein 1 |
| Other gene symbols | ARF1GAP HRIHFB2281 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0005096 | GTPase activator activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006890 | Retrograde vesicle-mediated transport, Golgi to ER | TAS | biological_process |
| GO:0006987 | Activation of signaling protein activity involved in unfolded protein response | TAS | biological_process |
| GO:0008060 | ARF GTPase activator activity | IEA | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0030660 | Golgi-associated vesicle membrane | TAS | cellular_component |
| GO:0030968 | Endoplasmic reticulum unfolded protein response | TAS | biological_process |
| GO:0031965 | Nuclear membrane | IDA | cellular_component |
| GO:0032312 | Regulation of ARF GTPase activity | IEA | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0043547 | Positive regulation of GTPase activity | IDA | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0045202 | Synapse | IEA | cellular_component |
| GO:0048205 | COPI coating of Golgi vesicle | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0974892861 | 0.8896751871 | 0.6529301527 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0837131517 |
| GSE13712_SHEAR | Up | 0.0677905142 |
| GSE13712_STATIC | Up | 0.3496640785 |
| GSE19018 | Up | 0.0789875023 |
| GSE19899_A1 | Up | 0.1185283116 |
| GSE19899_A2 | Up | 0.1778912986 |
| PubMed_21979375_A1 | Up | 1.4018678057 |
| PubMed_21979375_A2 | Up | 0.7652592030 |
| GSE35957 | Down | -0.5595342393 |
| GSE36640 | Up | 0.1902571514 |
| GSE54402 | Up | 0.3329505065 |
| GSE9593 | Down | -0.3924990894 |
| GSE43922 | Up | 0.2430347928 |
| GSE24585 | Down | -0.0345033294 |
| GSE37065 | Down | -0.1648627379 |
| GSE28863_A1 | Up | 0.0820329109 |
| GSE28863_A2 | Up | 0.0446661047 |
| GSE28863_A3 | Down | -0.0823898196 |
| GSE28863_A4 | Up | 0.0909899075 |
| GSE48662 | Up | 0.0650657712 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-93-3p | MIMAT0004509 | MIRT038909 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042628 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047930 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
