HCSGD entry for N4BP2
1. General information
| Official gene symbol | N4BP2 |
|---|---|
| Entrez ID | 55728 |
| Gene full name | NEDD4 binding protein 2 |
| Other gene symbols | B3BP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004519 | Endonuclease activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IDA | molecular_function |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0008152 | Metabolic process | IDA | biological_process |
| GO:0016310 | Phosphorylation | IDA | biological_process |
| GO:0046404 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity | IDA | molecular_function |
| GO:0090305 | Nucleic acid phosphodiester bond hydrolysis | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3831684814 | 0.0389038334 | 0.9999902473 | 0.3719534326 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1802893897 |
| GSE13712_SHEAR | Up | 0.2305421854 |
| GSE13712_STATIC | Up | 0.3765805299 |
| GSE19018 | Down | -0.6544193428 |
| GSE19899_A1 | Down | -0.0974339941 |
| GSE19899_A2 | Down | -1.1557415625 |
| PubMed_21979375_A1 | Up | 0.3381501155 |
| PubMed_21979375_A2 | Down | -0.0477067168 |
| GSE35957 | Down | -0.5407464018 |
| GSE36640 | Down | -1.1922263356 |
| GSE54402 | Up | 0.4168190973 |
| GSE9593 | Down | -0.6545996093 |
| GSE43922 | Down | -0.2092930583 |
| GSE24585 | Up | 0.5271182529 |
| GSE37065 | Down | -0.0490605499 |
| GSE28863_A1 | Up | 0.5046832026 |
| GSE28863_A2 | Down | -0.1315002548 |
| GSE28863_A3 | Down | -0.4989912949 |
| GSE28863_A4 | Down | -0.3080003722 |
| GSE48662 | Up | 0.2060559260 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-192-5p | MIMAT0000222 | MIRT026566 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048436 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-99a-5p | MIMAT0000097 | MIRT048611 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
