HCSGD entry for ASF1B


1. General information

Official gene symbolASF1B
Entrez ID55723
Gene full nameanti-silencing function 1B histone chaperone
Other gene symbolsCIA-II
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000785ChromatinIEAcellular_component
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006333Chromatin assembly or disassemblyIEAbiological_process
GO:0006334Nucleosome assemblyIEAbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0007283SpermatogenesisIEAbiological_process
GO:0016568Chromatin modificationIEAbiological_process
GO:0030154Cell differentiationIEAbiological_process
GO:0042393Histone bindingIEAmolecular_function
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.88300559630.00032002200.99999024730.0327754864

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.5151308614
GSE13712_SHEARDown-0.2999115542
GSE13712_STATICDown-0.4426651314
GSE19018Down-0.2076329985
GSE19899_A1Down-0.2829229476
GSE19899_A2Down-2.4932350761
PubMed_21979375_A1Down-1.2883013986
PubMed_21979375_A2Down-2.6252130675
GSE35957Down-1.9785572359
GSE36640Down-3.5355760033
GSE54402Down-0.1908049126
GSE9593Down-1.6130858525
GSE43922Down-1.7617472425
GSE24585Up0.5830734123
GSE37065Down-0.7496939992
GSE28863_A1Down-0.1583592436
GSE28863_A2Up1.1494918773
GSE28863_A3Up0.1369832900
GSE28863_A4Up0.1498451627
GSE48662Down-0.9449347210

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-193b-3pMIMAT0002819MIRT016454MicroarrayFunctional MTI (Weak)20304954
hsa-miR-26b-5pMIMAT0000083MIRT029781MicroarrayFunctional MTI (Weak)19088304
hsa-miR-214-3pMIMAT0000271MIRT035546Luciferase reporter assayFunctional MTI23100276
hsa-miR-130b-5pMIMAT0004680MIRT038280CLASHFunctional MTI (Weak)23622248
hsa-miR-92b-3pMIMAT0003218MIRT040666CLASHFunctional MTI (Weak)23622248
hsa-miR-18a-3pMIMAT0002891MIRT040934CLASHFunctional MTI (Weak)23622248
hsa-miR-324-5pMIMAT0000761MIRT043037CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

16980972The N- and C-terminal regions of ASF1a and ASF1b determine the different affinities of these two proteins for HIRA, by contacting regions outside the HIRA B domain
Entries Per Page
Displaying Page of