HCSGD entry for VAC14
1. General information
| Official gene symbol | VAC14 |
|---|---|
| Entrez ID | 55697 |
| Gene full name | Vac14 homolog (S. cerevisiae) |
| Other gene symbols | ArPIKfyve TAX1BP2 TRX |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | cellular_component |
| GO:0004872 | Receptor activity | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006661 | Phosphatidylinositol biosynthetic process | TAS | biological_process |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0010008 | Endosome membrane | IDA | cellular_component |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0019209 | Kinase activator activity | IEA | molecular_function |
| GO:0031901 | Early endosome membrane | TAS | cellular_component |
| GO:0031902 | Late endosome membrane | TAS | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4037953231 | 0.8243565708 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2547626541 |
| GSE13712_SHEAR | Up | 0.1782878752 |
| GSE13712_STATIC | Up | 0.1064057805 |
| GSE19018 | Up | 0.0328274629 |
| GSE19899_A1 | Down | -0.0482185185 |
| GSE19899_A2 | Up | 0.0361375540 |
| PubMed_21979375_A1 | Down | -0.1905328311 |
| PubMed_21979375_A2 | Up | 0.2141271934 |
| GSE35957 | Up | 0.0255256367 |
| GSE36640 | Down | -0.1248488154 |
| GSE54402 | Up | 0.3112483484 |
| GSE9593 | Up | 0.2209284266 |
| GSE43922 | Down | -0.1328629424 |
| GSE24585 | Down | -0.0959207695 |
| GSE37065 | Up | 0.0020900313 |
| GSE28863_A1 | Up | 0.1399169240 |
| GSE28863_A2 | Up | 0.4188570309 |
| GSE28863_A3 | Down | -0.1317607775 |
| GSE28863_A4 | Down | -0.1226467618 |
| GSE48662 | Up | 0.0831062450 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-429 | MIMAT0001536 | MIRT016639 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-200a-3p | MIMAT0000682 | MIRT020349 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-200c-3p | MIMAT0000617 | MIRT021072 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-141-3p | MIMAT0000432 | MIRT021651 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-200b-3p | MIMAT0000318 | MIRT024128 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-589-5p | MIMAT0004799 | MIRT037789 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038068 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-2-3p | MIMAT0004550 | MIRT038701 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
