HCSGD entry for RBM22
1. General information
| Official gene symbol | RBM22 |
|---|---|
| Entrez ID | 55696 |
| Gene full name | RNA binding motif protein 22 |
| Other gene symbols | Cwc2 ZC3H16 fSAP47 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000060 | Protein import into nucleus, translocation | IDA | biological_process |
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0000398 | MRNA splicing, via spliceosome | IC | biological_process |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005487 | Nucleocytoplasmic transporter activity | IDA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0017069 | SnRNA binding | IDA | molecular_function |
| GO:0033120 | Positive regulation of RNA splicing | IDA | biological_process |
| GO:0035690 | Cellular response to drug | IDA | biological_process |
| GO:0036002 | Pre-mRNA binding | IDA | molecular_function |
| GO:0045292 | MRNA cis splicing, via spliceosome | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0048306 | Calcium-dependent protein binding | IPI | molecular_function |
| GO:0071013 | Catalytic step 2 spliceosome | IDA | cellular_component |
| GO:0090316 | Positive regulation of intracellular protein transport | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2380877550 | 0.5591401087 | 0.9239457909 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2076902846 |
| GSE13712_SHEAR | Down | -0.0194413168 |
| GSE13712_STATIC | Down | -0.1818514773 |
| GSE19018 | Down | -0.2228335090 |
| GSE19899_A1 | Up | 0.1089376510 |
| GSE19899_A2 | Up | 0.3538891796 |
| PubMed_21979375_A1 | Up | 0.5829138597 |
| PubMed_21979375_A2 | Up | 0.1988978364 |
| GSE35957 | Down | -0.1452505123 |
| GSE36640 | Down | -0.2131180699 |
| GSE54402 | Up | 0.4545679639 |
| GSE9593 | Down | -0.2166085201 |
| GSE43922 | Up | 0.5214990191 |
| GSE24585 | Down | -0.0425851052 |
| GSE37065 | Up | 0.1180425648 |
| GSE28863_A1 | Up | 0.2514340900 |
| GSE28863_A2 | Up | 0.2521760200 |
| GSE28863_A3 | Down | -0.4529131715 |
| GSE28863_A4 | Down | -0.2588179923 |
| GSE48662 | Down | -0.4467324484 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020871 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052325 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
