HCSGD entry for SMEK1
1. General information
| Official gene symbol | SMEK1 |
|---|---|
| Entrez ID | 55671 |
| Gene full name | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| Other gene symbols | FLFL1 KIAA2010 PP4R3A smk-1 smk1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005815 | Microtubule organizing center | IEA | cellular_component |
| GO:0006470 | Protein dephosphorylation | IEA | biological_process |
| GO:0030289 | Protein phosphatase 4 complex | IEA | cellular_component |
| GO:0045722 | Positive regulation of gluconeogenesis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0695737092 | 0.9400349151 | 0.5643296148 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1932424792 |
| GSE13712_SHEAR | Up | 0.3988610690 |
| GSE13712_STATIC | Up | 0.1972430094 |
| GSE19018 | Up | 0.1246072404 |
| GSE19899_A1 | Up | 0.1843540662 |
| GSE19899_A2 | Down | -0.1536555575 |
| PubMed_21979375_A1 | Up | 0.5696020162 |
| PubMed_21979375_A2 | Up | 0.0722443095 |
| GSE35957 | Down | -0.5661259607 |
| GSE36640 | Down | -0.3667546375 |
| GSE54402 | Up | 0.1721310069 |
| GSE9593 | Down | -0.0055681670 |
| GSE43922 | Up | 0.0326228957 |
| GSE24585 | Up | 0.2759646204 |
| GSE37065 | Up | 0.1230518454 |
| GSE28863_A1 | Up | 0.7861335645 |
| GSE28863_A2 | Up | 0.5570333256 |
| GSE28863_A3 | Up | 0.1021423673 |
| GSE28863_A4 | Up | 0.1138852443 |
| GSE48662 | Down | -0.1636493192 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023969 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-183-5p | MIMAT0000261 | MIRT025023 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-30d-5p | MIMAT0000245 | MIRT047787 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
