HCSGD entry for CHD7
1. General information
| Official gene symbol | CHD7 |
|---|---|
| Entrez ID | 55636 |
| Gene full name | chromodomain helicase DNA binding protein 7 |
| Other gene symbols | HH5 IS3 KAL5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001501 | Skeletal system development | IMP | biological_process |
| GO:0001701 | In utero embryonic development | IEA IMP | biological_process |
| GO:0003007 | Heart morphogenesis | IEA IMP | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003682 | Chromatin binding | TAS | molecular_function |
| GO:0004386 | Helicase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA TAS | cellular_component |
| GO:0005730 | Nucleolus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | NAS | biological_process |
| GO:0006364 | RRNA processing | IEA | biological_process |
| GO:0007417 | Central nervous system development | IMP | biological_process |
| GO:0007512 | Adult heart development | IEA | biological_process |
| GO:0007605 | Sensory perception of sound | IEA | biological_process |
| GO:0007628 | Adult walking behavior | IEA | biological_process |
| GO:0008015 | Blood circulation | IEA | biological_process |
| GO:0016568 | Chromatin modification | IEA | biological_process |
| GO:0021545 | Cranial nerve development | IMP | biological_process |
| GO:0030217 | T cell differentiation | IMP | biological_process |
| GO:0030540 | Female genitalia development | IEA | biological_process |
| GO:0035116 | Embryonic hindlimb morphogenesis | IEA | biological_process |
| GO:0040018 | Positive regulation of multicellular organism growth | IEA | biological_process |
| GO:0042472 | Inner ear morphogenesis | IMP | biological_process |
| GO:0043010 | Camera-type eye development | IEA | biological_process |
| GO:0043584 | Nose development | IEA IMP | biological_process |
| GO:0048752 | Semicircular canal morphogenesis | IEA | biological_process |
| GO:0048806 | Genitalia development | IMP | biological_process |
| GO:0048844 | Artery morphogenesis | IEA | biological_process |
| GO:0050890 | Cognition | IMP | biological_process |
| GO:0060021 | Palate development | IEA IMP | biological_process |
| GO:0060041 | Retina development in camera-type eye | IMP | biological_process |
| GO:0060123 | Regulation of growth hormone secretion | IMP | biological_process |
| GO:0060173 | Limb development | IMP | biological_process |
| GO:0060324 | Face development | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0537305194 | 0.7304601345 | 0.5053903640 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0384861210 |
| GSE13712_SHEAR | Down | -0.0475340236 |
| GSE13712_STATIC | Up | 0.0396442621 |
| GSE19018 | Down | -0.0161047607 |
| GSE19899_A1 | Up | 0.2170874160 |
| GSE19899_A2 | Up | 0.6169404126 |
| PubMed_21979375_A1 | Up | 1.1585714693 |
| PubMed_21979375_A2 | Up | 0.8323992825 |
| GSE35957 | Down | -0.1880946401 |
| GSE36640 | Down | -0.1199696972 |
| GSE54402 | Up | 0.3212568200 |
| GSE9593 | Down | -0.1696356780 |
| GSE43922 | Up | 1.2805631125 |
| GSE24585 | Down | -0.6539299344 |
| GSE37065 | Down | -0.2391344861 |
| GSE28863_A1 | Up | 0.2595434435 |
| GSE28863_A2 | Up | 0.1350387869 |
| GSE28863_A3 | Up | 0.1634517247 |
| GSE28863_A4 | Up | 0.0424850975 |
| GSE48662 | Down | -0.0226526489 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024848 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026704 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027719 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037022 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-454-3p | MIMAT0003885 | MIRT039227 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039664 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051570 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052070 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
