HCSGD entry for G2E3


1. General information

Official gene symbolG2E3
Entrez ID55632
Gene full nameG2/M-phase specific E3 ubiquitin protein ligase
Other gene symbolsKIAA1333 PHF7B
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000209Protein polyubiquitinationIEAbiological_process
GO:0001824Blastocyst developmentIEAbiological_process
GO:0004842Ubiquitin-protein ligase activityIEAmolecular_function
GO:0005730NucleolusIEAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0006915Apoptotic processIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:2001243Negative regulation of intrinsic apoptotic signaling pathwayIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.99158386080.00194868740.99999024730.0846848435

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2605108296
GSE13712_SHEARDown-0.3419293774
GSE13712_STATICDown-0.3889353099
GSE19018Up0.0066839045
GSE19899_A1Down-0.2445362373
GSE19899_A2Down-1.2623305523
PubMed_21979375_A1Down-0.4798603863
PubMed_21979375_A2Down-1.2943232312
GSE35957Down-0.9677800505
GSE36640Down-1.6749727734
GSE54402Down-0.5921229485
GSE9593Down-0.8037775075
GSE43922Down-0.0153441591
GSE24585Down-0.3202008859
GSE37065Down-0.2923827631
GSE28863_A1Down-0.0842657425
GSE28863_A2Up0.2195908178
GSE28863_A3Down-1.0106147019
GSE28863_A4Up0.3416792484
GSE48662Down-0.5033312325

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017084MicroarrayFunctional MTI (Weak)18185580
hsa-miR-215-5pMIMAT0000272MIRT024882MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026908MicroarrayFunctional MTI (Weak)19074876
hsa-miR-186-5pMIMAT0000456MIRT044982CLASHFunctional MTI (Weak)23622248
hsa-miR-125a-5pMIMAT0000443MIRT045701CLASHFunctional MTI (Weak)23622248
hsa-let-7a-5pMIMAT0000062MIRT052552CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.