HCSGD entry for TRMT1
1. General information
| Official gene symbol | TRMT1 |
|---|---|
| Entrez ID | 55621 |
| Gene full name | tRNA methyltransferase 1 homolog (S. cerevisiae) |
| Other gene symbols | TRM1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000049 | TRNA binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0004809 | TRNA (guanine-N2-)-methyltransferase activity | IEA | molecular_function |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0370122716 | 0.8182017629 | 0.4364015514 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4422675948 |
| GSE13712_SHEAR | Up | 0.3268215497 |
| GSE13712_STATIC | Up | 0.4299876644 |
| GSE19018 | Down | -0.1667883105 |
| GSE19899_A1 | Up | 0.1940946316 |
| GSE19899_A2 | Up | 0.9273315037 |
| PubMed_21979375_A1 | Up | 1.3653758969 |
| PubMed_21979375_A2 | Up | 1.0178874289 |
| GSE35957 | Down | -0.1577531654 |
| GSE36640 | Up | 0.0472863986 |
| GSE54402 | Up | 0.2440467606 |
| GSE9593 | Down | -0.1137283705 |
| GSE43922 | Up | 0.5169479343 |
| GSE24585 | Down | -0.8204230052 |
| GSE37065 | Down | -0.2231826243 |
| GSE28863_A1 | Up | 0.0402216924 |
| GSE28863_A2 | Down | -0.0597751409 |
| GSE28863_A3 | Up | 0.1510072709 |
| GSE28863_A4 | Up | 0.0565593938 |
| GSE48662 | Down | -0.0931980062 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT001584 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020603 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031488 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
