HCSGD entry for DOCK10
1. General information
| Official gene symbol | DOCK10 |
|---|---|
| Entrez ID | 55619 |
| Gene full name | dedicator of cytokinesis 10 |
| Other gene symbols | DRIP2 Nbla10300 ZIZ3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005085 | Guanyl-nucleotide exchange factor activity | IEA | molecular_function |
| GO:0005089 | Rho guanyl-nucleotide exchange factor activity | IEA | molecular_function |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0017048 | Rho GTPase binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1686264086 | 0.0499457239 | 0.8090845060 | 0.4181365776 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0839166324 |
| GSE13712_SHEAR | Up | 0.3140603189 |
| GSE13712_STATIC | Up | 0.4958483227 |
| GSE19018 | Down | -0.4936845504 |
| GSE19899_A1 | Down | -0.0378168601 |
| GSE19899_A2 | Down | -0.6046418569 |
| PubMed_21979375_A1 | Down | -0.9365611071 |
| PubMed_21979375_A2 | Down | -0.4505338441 |
| GSE35957 | Down | -1.0461661560 |
| GSE36640 | Down | -0.2339482827 |
| GSE54402 | Up | 0.5301452528 |
| GSE9593 | Up | 0.0461774423 |
| GSE43922 | Down | -0.1700508178 |
| GSE24585 | Up | 0.2468392942 |
| GSE37065 | Up | 0.0424847642 |
| GSE28863_A1 | Up | 0.9032748258 |
| GSE28863_A2 | Up | 1.3167640950 |
| GSE28863_A3 | Down | -0.8170926576 |
| GSE28863_A4 | Up | 0.0450632288 |
| GSE48662 | Down | -0.4403812342 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-142-3p | MIMAT0000434 | MIRT021604 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-132-3p | MIMAT0000426 | MIRT021826 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029588 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030887 | Microarray | Functional MTI (Weak) | 18591254 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
