HCSGD entry for DOCK10


1. General information

Official gene symbolDOCK10
Entrez ID55619
Gene full namededicator of cytokinesis 10
Other gene symbolsDRIP2 Nbla10300 ZIZ3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005085Guanyl-nucleotide exchange factor activityIEAmolecular_function
GO:0005089Rho guanyl-nucleotide exchange factor activityIEAmolecular_function
GO:0007264Small GTPase mediated signal transductionIEAbiological_process
GO:0017048Rho GTPase bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.16862640860.04994572390.80908450600.4181365776

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0839166324
GSE13712_SHEARUp0.3140603189
GSE13712_STATICUp0.4958483227
GSE19018Down-0.4936845504
GSE19899_A1Down-0.0378168601
GSE19899_A2Down-0.6046418569
PubMed_21979375_A1Down-0.9365611071
PubMed_21979375_A2Down-0.4505338441
GSE35957Down-1.0461661560
GSE36640Down-0.2339482827
GSE54402Up0.5301452528
GSE9593Up0.0461774423
GSE43922Down-0.1700508178
GSE24585Up0.2468392942
GSE37065Up0.0424847642
GSE28863_A1Up0.9032748258
GSE28863_A2Up1.3167640950
GSE28863_A3Down-0.8170926576
GSE28863_A4Up0.0450632288
GSE48662Down-0.4403812342

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-142-3pMIMAT0000434MIRT021604MicroarrayFunctional MTI (Weak)17612493
hsa-miR-132-3pMIMAT0000426MIRT021826MicroarrayFunctional MTI (Weak)17612493
hsa-miR-26b-5pMIMAT0000083MIRT029588MicroarrayFunctional MTI (Weak)19088304
hsa-miR-21-5pMIMAT0000076MIRT030887MicroarrayFunctional MTI (Weak)18591254
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.