HCSGD entry for DDX60
1. General information
Official gene symbol | DDX60 |
---|---|
Entrez ID | 55601 |
Gene full name | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
Other gene symbols | |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
![color bar](img/red_blue.jpg)
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0003690 | Double-stranded DNA binding | IDA | molecular_function |
GO:0003723 | RNA binding | IEA | molecular_function |
GO:0003725 | Double-stranded RNA binding | IDA | molecular_function |
GO:0003727 | Single-stranded RNA binding | IDA | molecular_function |
GO:0005515 | Protein binding | IPI | molecular_function |
GO:0005524 | ATP binding | IEA | molecular_function |
GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
GO:0008026 | ATP-dependent helicase activity | IEA | molecular_function |
GO:0009615 | Response to virus | IDA | biological_process |
GO:0045087 | Innate immune response | IEA | biological_process |
GO:0051607 | Defense response to virus | IEA | biological_process |
GO:1900245 | Positive regulation of MDA-5 signaling pathway | IMP | biological_process |
GO:1900246 | Positive regulation of RIG-I signaling pathway | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.0071198777 | 0.0059056533 | 0.2204732941 | 0.1551324351 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | Up | 0.0031003250 |
GSE13712_SHEAR | Up | 1.8830821564 |
GSE13712_STATIC | Up | 1.3133051989 |
GSE19018 | Down | -0.0270743193 |
GSE19899_A1 | Down | -0.7348487655 |
GSE19899_A2 | Down | -2.1864281982 |
PubMed_21979375_A1 | Down | -1.4869154065 |
PubMed_21979375_A2 | Down | -1.9421831395 |
GSE35957 | Down | -1.8381263090 |
GSE36640 | Up | 1.3197839992 |
GSE54402 | Down | -0.9886553928 |
GSE9593 | Up | 0.2067555986 |
GSE43922 | Down | -1.5899945511 |
GSE24585 | Up | 1.4985620425 |
GSE37065 | Up | 1.0433480343 |
GSE28863_A1 | Up | 1.0618345330 |
GSE28863_A2 | Up | 2.2663093945 |
GSE28863_A3 | Down | -0.6247417070 |
GSE28863_A4 | Down | -0.1821349651 |
GSE48662 | Down | -0.5301389067 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
---|---|---|---|---|---|
hsa-miR-1 | MIMAT0000416 | MIRT023901 | Microarray | Functional MTI (Weak) | 18668037 |
hsa-miR-26b-5p | MIMAT0000083 | MIRT029819 | Microarray | Functional MTI (Weak) | 19088304 |
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