HCSGD entry for ITLN1


1. General information

Official gene symbolITLN1
Entrez ID55600
Gene full nameintelectin 1 (galactofuranose binding)
Other gene symbolsHL-1 HL1 INTL ITLN LFR hIntL omentin
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001934Positive regulation of protein phosphorylationIDAbiological_process
GO:0005576Extracellular regionIEAcellular_component
GO:0009624Response to nematodeISSbiological_process
GO:0031225Anchored component of membraneIEAcellular_component
GO:0031526Brush border membraneISScellular_component
GO:0043235Receptor complexIDAcellular_component
GO:0045121Membrane raftISScellular_component
GO:0046326Positive regulation of glucose importIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.79476173020.76592147710.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1549822988
GSE13712_SHEARDown-0.1413997868
GSE13712_STATICUp0.0903836953
GSE19018Up0.0749440987
GSE19899_A1Down-0.0304298425
GSE19899_A2Up0.0801954616
PubMed_21979375_A1Down-0.0102007224
PubMed_21979375_A2Up0.1076808068
GSE35957Up0.0160109589
GSE36640Down-0.0478106615
GSE54402Up0.0826810710
GSE9593Up0.0058484794
GSE43922Up0.0167927177
GSE24585Up0.2392974269
GSE37065Down-0.0454141170
GSE28863_A1Up0.0227614898
GSE28863_A2Up0.0631496366
GSE28863_A3Up0.0718774896
GSE28863_A4Down-0.0990030645
GSE48662Up0.0299016916

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

25543718In the present study, we evaluated the effects of IR on HL-1 and H9C2 cells, cells predominantly used in in vitro myocardial cell models
25543718We found that the exposure of the HL-1 and H9C2 cells to IR induced reactive oxygen species (ROS)-mediated cellular senescence, as shown by staining of senescence-associated beta-galactosidase (SA-beta-gal)
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