HCSGD entry for OTUD5
1. General information
| Official gene symbol | OTUD5 |
|---|---|
| Entrez ID | 55593 |
| Gene full name | OTU domain containing 5 |
| Other gene symbols | DUBA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004843 | Ubiquitin-specific protease activity | IDA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0032480 | Negative regulation of type I interferon production | TAS | biological_process |
| GO:0032496 | Response to lipopolysaccharide | IDA | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0070536 | Protein K63-linked deubiquitination | IDA | biological_process |
| GO:0071108 | Protein K48-linked deubiquitination | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2549465978 | 0.7624030394 | 0.9463332957 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0334834585 |
| GSE13712_SHEAR | Down | -0.0361754408 |
| GSE13712_STATIC | Down | -0.2693348750 |
| GSE19018 | Up | 0.2962432352 |
| GSE19899_A1 | Up | 0.0317434696 |
| GSE19899_A2 | Up | 0.4427375065 |
| PubMed_21979375_A1 | Up | 0.5160214584 |
| PubMed_21979375_A2 | Up | 0.1080581189 |
| GSE35957 | Down | -0.0094161237 |
| GSE36640 | Up | 0.3340814525 |
| GSE54402 | Up | 0.3403271737 |
| GSE9593 | Down | -0.0258852625 |
| GSE43922 | Up | 0.0265255569 |
| GSE24585 | Down | -0.0064178435 |
| GSE37065 | Down | -0.0822560814 |
| GSE28863_A1 | Up | 0.0596724891 |
| GSE28863_A2 | Down | -0.2015957539 |
| GSE28863_A3 | Down | -0.0656908304 |
| GSE28863_A4 | Down | -0.0797748068 |
| GSE48662 | Up | 0.1067388390 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-505-3p | MIMAT0002876 | MIRT041070 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-339-5p | MIMAT0000764 | MIRT042795 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-328-3p | MIMAT0000752 | MIRT043793 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051503 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-1260b | MIMAT0015041 | MIRT052692 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
