HCSGD entry for PRIM2

1. General information

Official gene symbolPRIM2
Entrez ID5558
Gene full nameprimase, DNA, polypeptide 2 (58kDa)
Other gene symbolsPRIM2A p58
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000082G1/S transition of mitotic cell cycleTASbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0000722Telomere maintenance via recombinationTASbiological_process
GO:0000723Telomere maintenanceTASbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0003896DNA primase activityIEAmolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0006269DNA replication, synthesis of RNA primerTASbiological_process
GO:0006270DNA replication initiationTASbiological_process
GO:0006271DNA strand elongation involved in DNA replicationTASbiological_process
GO:0032201Telomere maintenance via semi-conservative replicationTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:00515394 iron, 4 sulfur cluster bindingIEAmolecular_function
GO:1990077Primosome complexIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.98586388440.00787852670.99999024730.1775434075

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1867766218
GSE13712_SHEARUp0.2641370259
GSE13712_STATICUp0.1823570772
GSE19018Down-0.1442044079
GSE19899_A1Down-0.2923498654
GSE19899_A2Down-1.0861984718
PubMed_21979375_A1Down-1.1837760951
PubMed_21979375_A2Down-1.9428212505
GSE35957Down-0.1497289608
GSE36640Down-0.9244357669
GSE54402Down-0.2876211523
GSE9593Up0.1843958212
GSE43922Down-0.6322492604
GSE24585Down-0.0127740494
GSE37065Down-0.2916551401
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.5246976929

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.