HCSGD entry for NAGK
1. General information
| Official gene symbol | NAGK |
|---|---|
| Entrez ID | 55577 |
| Gene full name | N-acetylglucosamine kinase |
| Other gene symbols | GNK HSA242910 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0006044 | N-acetylglucosamine metabolic process | IEA | biological_process |
| GO:0006051 | N-acetylmannosamine metabolic process | TAS | biological_process |
| GO:0009384 | N-acylmannosamine kinase activity | IEA | molecular_function |
| GO:0019262 | N-acetylneuraminate catabolic process | IEA TAS | biological_process |
| GO:0045127 | N-acetylglucosamine kinase activity | IDA IEA | molecular_function |
| GO:0046835 | Carbohydrate phosphorylation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2263658600 | 0.1676171460 | 0.9079416083 | 0.7916473892 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.8767111958 |
| GSE13712_SHEAR | Up | 0.0937571469 |
| GSE13712_STATIC | Up | 0.1197833536 |
| GSE19018 | Up | 0.2314756989 |
| GSE19899_A1 | Down | -0.3759170858 |
| GSE19899_A2 | Down | -0.5962024934 |
| PubMed_21979375_A1 | Up | 0.3728066946 |
| PubMed_21979375_A2 | Down | -0.9567120314 |
| GSE35957 | Down | -0.5629315016 |
| GSE36640 | Up | 0.3237465268 |
| GSE54402 | Up | 0.1855614369 |
| GSE9593 | Up | 0.6818024582 |
| GSE43922 | Down | -0.0977166104 |
| GSE24585 | Up | 0.2630928503 |
| GSE37065 | Up | 0.0408318254 |
| GSE28863_A1 | Down | -0.5521817572 |
| GSE28863_A2 | Up | 0.0943254988 |
| GSE28863_A3 | Down | -0.2410743980 |
| GSE28863_A4 | Down | -0.1466554006 |
| GSE48662 | Up | 0.1318826026 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| N-Acetyl-D-glucosamine | DB00141 | NUTR00040 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028866 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050916 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
