HCSGD entry for STRADB
1. General information
| Official gene symbol | STRADB |
|---|---|
| Entrez ID | 55437 |
| Gene full name | STE20-related kinase adaptor beta |
| Other gene symbols | ALS2CR2 CALS-21 ILPIP ILPIPA PAPK |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000902 | Cell morphogenesis | IEA | biological_process |
| GO:0004672 | Protein kinase activity | IDA IEA | molecular_function |
| GO:0004702 | Receptor signaling protein serine/threonine kinase activity | IBA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006468 | Protein phosphorylation | IDA | biological_process |
| GO:0006611 | Protein export from nucleus | IDA | biological_process |
| GO:0007050 | Cell cycle arrest | TAS | biological_process |
| GO:0007254 | JNK cascade | IEA | biological_process |
| GO:0008286 | Insulin receptor signaling pathway | TAS | biological_process |
| GO:0016772 | Transferase activity, transferring phosphorus-containing groups | IEA | molecular_function |
| GO:0032147 | Activation of protein kinase activity | IDA | biological_process |
| GO:2001240 | Negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9003108886 | 0.0373096691 | 0.9999902473 | 0.3640844329 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0201086009 |
| GSE13712_SHEAR | Down | -0.0421694604 |
| GSE13712_STATIC | Up | 0.1405201483 |
| GSE19018 | Up | 0.3017896016 |
| GSE19899_A1 | Down | -0.8536947087 |
| GSE19899_A2 | Down | -0.0641354108 |
| PubMed_21979375_A1 | Down | -0.2704824462 |
| PubMed_21979375_A2 | Down | -0.2588375519 |
| GSE35957 | Down | -0.2160066100 |
| GSE36640 | Down | -0.1342510476 |
| GSE54402 | Down | -0.2590762208 |
| GSE9593 | Up | 0.7698549903 |
| GSE43922 | Down | -0.4354178312 |
| GSE24585 | Down | -0.2775956195 |
| GSE37065 | Up | 0.0872911069 |
| GSE28863_A1 | Down | -0.2391637798 |
| GSE28863_A2 | Up | 0.1170971595 |
| GSE28863_A3 | Down | -0.2466296089 |
| GSE28863_A4 | Down | -0.1259301154 |
| GSE48662 | Down | -0.5847021263 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26a-5p | MIMAT0000082 | MIRT004339 | Western blot | Non-Functional MTI | 18713946 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016295 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030416 | Microarray | Functional MTI (Weak) | 19748357 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | NA | hsa-miR-26b | 20831567 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
