HCSGD entry for MEG3

1. General information

Official gene symbolMEG3
Entrez ID55384
Gene full namematernally expressed 3 (non-protein coding)
Other gene symbolsFP504 GTL2 LINC00023 NCRNA00023 PRO0518 PRO2160 prebp1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003713Transcription coactivator activityIDAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0007411Axon guidanceISSbiological_process
GO:0008285Negative regulation of cell proliferationIDAbiological_process
GO:0016525Negative regulation of angiogenesisISSbiological_process
GO:0030154Cell differentiationISSbiological_process
GO:0030948Negative regulation of vascular endothelial growth factor receptor signaling pathwayISSbiological_process
GO:0032274Gonadotropin secretionIEP IMPbiological_process
GO:0034337RNA foldingIDAbiological_process
GO:0040019Positive regulation of embryonic developmentISSbiological_process
GO:0044029Hypomethylation of CpG islandISSbiological_process
GO:0045746Negative regulation of Notch signaling pathwayISSbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIDA ISSbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDA ISSbiological_process
GO:0048743Positive regulation of skeletal muscle fiber developmentISSbiological_process
GO:2000279Negative regulation of DNA biosynthetic processIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.06677914590.84428509560.55623477851.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1463973391
GSE13712_SHEARUp1.0592400990
GSE13712_STATICUp0.4612557049
GSE19018Down-0.2243492499
GSE19899_A1Down-0.0351752708
GSE19899_A2Up0.2153742061
PubMed_21979375_A1Down-0.2663458691
PubMed_21979375_A2Up0.2742374913
GSE35957Down-0.0712656480
GSE36640Up1.3895126083
GSE54402Up0.2118174371
GSE9593Up0.2423760945
GSE43922Up0.2161853120
GSE24585Down-0.1891792616
GSE37065Up0.0200496573
GSE28863_A1Down-0.1009729352
GSE28863_A2Up0.0986644730
GSE28863_A3Up0.2028773739
GSE28863_A4Up0.0267862452
GSE48662Up0.0376511210

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.