HCSGD entry for ACER3

1. General information

Official gene symbolACER3
Entrez ID55331
Gene full namealkaline ceramidase 3
Other gene symbolsAPHC PHCA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0006665Sphingolipid metabolic processTASbiological_process
GO:0006672Ceramide metabolic processIEAbiological_process
GO:0008284Positive regulation of cell proliferationIMPbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016811Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidesIEAmolecular_function
GO:0030148Sphingolipid biosynthetic processTASbiological_process
GO:0030173Integral component of Golgi membraneIDAcellular_component
GO:0030176Integral component of endoplasmic reticulum membraneIDAcellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046512Sphingosine biosynthetic processIDAbiological_process
GO:0070774Phytoceramidase activityIDAmolecular_function
GO:0071602Phytosphingosine biosynthetic processIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.09989900460.41461040610.65950381241.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1701929201
GSE13712_SHEARDown-0.0704472829
GSE13712_STATICUp0.3826577796
GSE19018Down-0.3976304507
GSE19899_A1Down-0.1907635373
GSE19899_A2Up0.2516320269
PubMed_21979375_A1Up1.0139791118
PubMed_21979375_A2Up0.2597785391
GSE35957Down-0.3886907218
GSE36640Down-0.9035670799
GSE54402Up0.4540449630
GSE9593Down-0.0618048528
GSE43922Up0.1035924186
GSE24585Up0.4234573611
GSE37065Down-0.0711509430
GSE28863_A1Up0.6324794431
GSE28863_A2Up0.5810348150
GSE28863_A3Down-0.6011818455
GSE28863_A4Down-0.0206546718
GSE48662Down-0.2938359946

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-30b-5pMIMAT0000420MIRT046140CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.