HCSGD entry for AP5S1
1. General information
| Official gene symbol | AP5S1 |
|---|---|
| Entrez ID | 55317 |
| Gene full name | adaptor-related protein complex 5, sigma 1 subunit |
| Other gene symbols | C20orf29 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000724 | Double-strand break repair via homologous recombination | IMP | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005764 | Lysosome | IDA | cellular_component |
| GO:0005765 | Lysosomal membrane | IEA | cellular_component |
| GO:0005770 | Late endosome | IDA | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016197 | Endosomal transport | IMP | biological_process |
| GO:0030119 | AP-type membrane coat adaptor complex | IDA | cellular_component |
| GO:0031902 | Late endosome membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5700653205 | 0.2727185099 | 0.9999902473 | 0.9987342329 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0109585222 |
| GSE13712_SHEAR | Up | 0.1585660826 |
| GSE13712_STATIC | Up | 0.1918643639 |
| GSE19018 | Up | 0.0331780863 |
| GSE19899_A1 | Down | -0.3151558041 |
| GSE19899_A2 | Up | 0.3512116311 |
| PubMed_21979375_A1 | Up | 0.1531629482 |
| PubMed_21979375_A2 | Up | 0.5590114997 |
| GSE35957 | Up | 0.2428986247 |
| GSE36640 | Up | 0.1888027461 |
| GSE54402 | Down | -0.1022245488 |
| GSE9593 | Down | -0.1085510945 |
| GSE43922 | Up | 0.0479069645 |
| GSE24585 | Down | -0.1186890031 |
| GSE37065 | Down | -0.3021533804 |
| GSE28863_A1 | Up | 0.0161513819 |
| GSE28863_A2 | Down | -0.1675351712 |
| GSE28863_A3 | Down | -0.2593243876 |
| GSE28863_A4 | Down | -0.2437440792 |
| GSE48662 | Down | -0.1458486493 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046383 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047741 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
