HCSGD entry for RFK
1. General information
| Official gene symbol | RFK |
|---|---|
| Entrez ID | 55312 |
| Gene full name | riboflavin kinase |
| Other gene symbols | RIFK |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | NAS | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006766 | Vitamin metabolic process | TAS | biological_process |
| GO:0006767 | Water-soluble vitamin metabolic process | TAS | biological_process |
| GO:0006771 | Riboflavin metabolic process | TAS | biological_process |
| GO:0006915 | Apoptotic process | IMP | biological_process |
| GO:0008531 | Riboflavin kinase activity | IEA NAS TAS | molecular_function |
| GO:0009231 | Riboflavin biosynthetic process | IEA NAS | biological_process |
| GO:0009398 | FMN biosynthetic process | IEA | biological_process |
| GO:0033864 | Positive regulation of NAD(P)H oxidase activity | IMP | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0409881425 | 0.8002111850 | 0.4536791001 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.8171685459 |
| GSE13712_SHEAR | Down | -0.1854127849 |
| GSE13712_STATIC | Down | -0.1240982566 |
| GSE19018 | Up | 0.2490958043 |
| GSE19899_A1 | Up | 0.4700928523 |
| GSE19899_A2 | Up | 0.6031099260 |
| PubMed_21979375_A1 | Up | 0.7096546195 |
| PubMed_21979375_A2 | Up | 0.4864159702 |
| GSE35957 | Down | -0.2846945821 |
| GSE36640 | Up | 0.3356480590 |
| GSE54402 | Up | 0.0444410454 |
| GSE9593 | Down | -0.0931842295 |
| GSE43922 | Up | 0.1784926550 |
| GSE24585 | Down | -0.5454249962 |
| GSE37065 | Up | 0.2135112734 |
| GSE28863_A1 | Down | -0.2050159048 |
| GSE28863_A2 | Down | -0.1891725450 |
| GSE28863_A3 | Up | 0.1930853706 |
| GSE28863_A4 | Up | 0.3276814842 |
| GSE48662 | Down | -0.1232879619 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Riboflavin Monophosphate | DB03247 | EXPT01458 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-186-5p | MIMAT0000456 | MIRT021169 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027183 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031929 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
