HCSGD entry for RHOT1
1. General information
| Official gene symbol | RHOT1 |
|---|---|
| Entrez ID | 55288 |
| Gene full name | ras homolog family member T1 |
| Other gene symbols | ARHT1 MIRO-1 MIRO1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005741 | Mitochondrial outer membrane | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007264 | Small GTPase mediated signal transduction | IEA TAS | biological_process |
| GO:0019725 | Cellular homeostasis | IEA IMP | biological_process |
| GO:0031307 | Integral component of mitochondrial outer membrane | IDA | cellular_component |
| GO:0047497 | Mitochondrion transport along microtubule | IMP | biological_process |
| GO:0051056 | Regulation of small GTPase mediated signal transduction | TAS | biological_process |
| GO:0097345 | Mitochondrial outer membrane permeabilization | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8471904867 | 0.4588184529 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0108346702 |
| GSE13712_SHEAR | Down | -0.1469463714 |
| GSE13712_STATIC | Down | -0.0550180166 |
| GSE19018 | Up | 0.5728035672 |
| GSE19899_A1 | Down | -0.1290355288 |
| GSE19899_A2 | Down | -0.0137717515 |
| PubMed_21979375_A1 | Down | -0.2184150059 |
| PubMed_21979375_A2 | Down | -0.0600411275 |
| GSE35957 | Down | -0.1291177020 |
| GSE36640 | Up | 0.2371655048 |
| GSE54402 | Down | -0.1142143173 |
| GSE9593 | Down | -0.0953362574 |
| GSE43922 | Down | -0.0568060634 |
| GSE24585 | Up | 0.0824685743 |
| GSE37065 | Up | 0.0672835883 |
| GSE28863_A1 | Down | -0.0691557846 |
| GSE28863_A2 | Down | -0.1301406297 |
| GSE28863_A3 | Up | 0.0901146274 |
| GSE28863_A4 | Down | -0.0334201070 |
| GSE48662 | Down | -0.0477593379 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT000899 | Microarray | Functional MTI (Weak) | 18362358 |
| hsa-miR-15a-5p | MIMAT0000068 | MIRT000900 | Microarray | Functional MTI (Weak) | 18362358 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT018247 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036811 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-15a-5p | MIMAT0000068 | NA | hsa-miR-15a | 18362358 | |||
| hsa-miR-16-5p | MIMAT0000069 | NA | hsa-miR-16 | 18362358 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
