HCSGD entry for VPS53


1. General information

Official gene symbolVPS53
Entrez ID55275
Gene full namevacuolar protein sorting 53 homolog (S. cerevisiae)
Other gene symbolsHCCS1 hVps53L pp13624
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000938GARP complexIDAcellular_component
GO:0005515Protein bindingIPImolecular_function
GO:0010008Endosome membraneIEAcellular_component
GO:0015031Protein transportIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.08659204440.97618146350.61736863491.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0636614669
GSE13712_SHEARUp0.0995760688
GSE13712_STATICUp0.0598002323
GSE19018Down-0.0373508924
GSE19899_A1Up0.1227202700
GSE19899_A2Up0.3668095541
PubMed_21979375_A1Up0.3154372698
PubMed_21979375_A2Up0.5002178748
GSE35957Up0.1477188252
GSE36640Up0.6504077596
GSE54402Up0.2818587073
GSE9593Up0.3979785712
GSE43922Down-0.0415517046
GSE24585Up0.0233542321
GSE37065Down-0.1438895532
GSE28863_A1Up0.5571421518
GSE28863_A2Up0.2206082791
GSE28863_A3Down-0.0561800283
GSE28863_A4Down-0.0623084801
GSE48662Up0.1497894437

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT023608ProteomicsFunctional MTI (Weak)18668040
hsa-miR-877-3pMIMAT0004950MIRT036899CLASHFunctional MTI (Weak)23622248
hsa-miR-28-3pMIMAT0004502MIRT038949CLASHFunctional MTI (Weak)23622248
hsa-miR-328-3pMIMAT0000752MIRT043781CLASHFunctional MTI (Weak)23622248
hsa-miR-221-3pMIMAT0000278MIRT046870CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.