HCSGD entry for NUDT15
1. General information
| Official gene symbol | NUDT15 |
|---|---|
| Entrez ID | 55270 |
| Gene full name | nudix (nucleoside diphosphate linked moiety X)-type motif 15 |
| Other gene symbols | MTH2 RP11-90M2.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006184 | GTP catabolic process | IDA | biological_process |
| GO:0006203 | DGTP catabolic process | IDA | biological_process |
| GO:0008413 | 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity | IDA | molecular_function |
| GO:0034656 | Nucleobase-containing small molecule catabolic process | TAS | biological_process |
| GO:0035539 | 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity | IDA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0055086 | Nucleobase-containing small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9800671289 | 0.0064820296 | 0.9999902473 | 0.1636646226 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2025847105 |
| GSE13712_SHEAR | Up | 0.4925891833 |
| GSE13712_STATIC | Up | 0.0579482878 |
| GSE19018 | Down | -0.7538805475 |
| GSE19899_A1 | Down | -1.0064140792 |
| GSE19899_A2 | Down | -0.6516595185 |
| PubMed_21979375_A1 | Down | -0.4545824552 |
| PubMed_21979375_A2 | Down | -1.0369200450 |
| GSE35957 | Down | -0.7935787016 |
| GSE36640 | Down | -1.6686313930 |
| GSE54402 | Down | -0.0499755543 |
| GSE9593 | Down | -0.7356007237 |
| GSE43922 | Down | -0.0606489154 |
| GSE24585 | Down | -0.0698201933 |
| GSE37065 | Down | -0.2681081737 |
| GSE28863_A1 | Down | -0.0922116614 |
| GSE28863_A2 | Up | 0.0865758627 |
| GSE28863_A3 | Up | 0.0210367374 |
| GSE28863_A4 | Up | 0.2422472189 |
| GSE48662 | Down | -0.6179544864 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024551 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026659 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051689 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
