HCSGD entry for NUDT15


1. General information

Official gene symbolNUDT15
Entrez ID55270
Gene full namenudix (nucleoside diphosphate linked moiety X)-type motif 15
Other gene symbolsMTH2 RP11-90M2.1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005829CytosolTAScellular_component
GO:0006184GTP catabolic processIDAbiological_process
GO:0006203DGTP catabolic processIDAbiological_process
GO:00084138-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activityIDAmolecular_function
GO:0034656Nucleobase-containing small molecule catabolic processTASbiological_process
GO:00355398-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activityIDAmolecular_function
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0055086Nucleobase-containing small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.98006712890.00648202960.99999024730.1636646226

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2025847105
GSE13712_SHEARUp0.4925891833
GSE13712_STATICUp0.0579482878
GSE19018Down-0.7538805475
GSE19899_A1Down-1.0064140792
GSE19899_A2Down-0.6516595185
PubMed_21979375_A1Down-0.4545824552
PubMed_21979375_A2Down-1.0369200450
GSE35957Down-0.7935787016
GSE36640Down-1.6686313930
GSE54402Down-0.0499755543
GSE9593Down-0.7356007237
GSE43922Down-0.0606489154
GSE24585Down-0.0698201933
GSE37065Down-0.2681081737
GSE28863_A1Down-0.0922116614
GSE28863_A2Up0.0865758627
GSE28863_A3Up0.0210367374
GSE28863_A4Up0.2422472189
GSE48662Down-0.6179544864

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-215-5pMIMAT0000272MIRT024551MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026659MicroarrayFunctional MTI (Weak)19074876
hsa-let-7e-5pMIMAT0000066MIRT051689CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.