HCSGD entry for MRGBP
1. General information
| Official gene symbol | MRGBP |
|---|---|
| Entrez ID | 55257 |
| Gene full name | MRG/MORF4L binding protein |
| Other gene symbols | C20orf20 Eaf7 MRG15BP URCC4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0016568 | Chromatin modification | IEA | biological_process |
| GO:0040008 | Regulation of growth | IEA | biological_process |
| GO:0043189 | H4/H2A histone acetyltransferase complex | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1527271532 | 0.5656216063 | 0.7798500872 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2360791504 |
| GSE13712_SHEAR | Up | 0.1726297999 |
| GSE13712_STATIC | Up | 0.2421387671 |
| GSE19018 | Up | 0.1983447634 |
| GSE19899_A1 | Up | 0.1050864850 |
| GSE19899_A2 | Up | 0.8904775342 |
| PubMed_21979375_A1 | Up | 0.8373148932 |
| PubMed_21979375_A2 | Up | 0.3824830297 |
| GSE35957 | Down | -0.7257841691 |
| GSE36640 | Down | -0.3550984119 |
| GSE54402 | Up | 0.4833775790 |
| GSE9593 | Down | -0.1797832148 |
| GSE43922 | Up | 0.2382807148 |
| GSE24585 | Down | -0.3149329296 |
| GSE37065 | Down | -0.2290126445 |
| GSE28863_A1 | Up | 0.0579007142 |
| GSE28863_A2 | Up | 0.0379989857 |
| GSE28863_A3 | Up | 0.0959338682 |
| GSE28863_A4 | Up | 0.1413019135 |
| GSE48662 | Down | -0.2526091315 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-101-3p | MIMAT0000099 | MIRT027304 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-503-5p | MIMAT0002874 | MIRT041119 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049387 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 16407074 | Site-directed mutagenesis studies based on the X-ray structure and bioinformatics identified key residues involved in the binding of PAM14 and MRGBP |
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