HCSGD entry for ELP2
1. General information
| Official gene symbol | ELP2 |
|---|---|
| Entrez ID | 55250 |
| Gene full name | elongator acetyltransferase complex subunit 2 |
| Other gene symbols | SHINC-2 STATIP1 StIP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0005730 | Nucleolus | IC | cellular_component |
| GO:0005737 | Cytoplasm | IDA NAS | cellular_component |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006368 | Transcription elongation from RNA polymerase II promoter | IC | biological_process |
| GO:0008023 | Transcription elongation factor complex | IDA | cellular_component |
| GO:0016591 | DNA-directed RNA polymerase II, holoenzyme | IC | cellular_component |
| GO:0019901 | Protein kinase binding | IEA | molecular_function |
| GO:0033588 | Elongator holoenzyme complex | IDA | cellular_component |
| GO:0046425 | Regulation of JAK-STAT cascade | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6887844991 | 0.1281013563 | 0.9999902473 | 0.6898027414 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0664666816 |
| GSE13712_SHEAR | Down | -0.0857038962 |
| GSE13712_STATIC | Up | 0.1063572755 |
| GSE19018 | Up | 0.0163472201 |
| GSE19899_A1 | Down | -0.1335144814 |
| GSE19899_A2 | Down | -0.2649135312 |
| PubMed_21979375_A1 | Down | -0.6522931451 |
| PubMed_21979375_A2 | Down | -0.3687148900 |
| GSE35957 | Up | 0.3862972181 |
| GSE36640 | Up | 0.4524862926 |
| GSE54402 | Down | -0.1295783950 |
| GSE9593 | Up | 0.3490424409 |
| GSE43922 | Up | 0.0021822864 |
| GSE24585 | Down | -0.4878346255 |
| GSE37065 | Down | -0.1115768306 |
| GSE28863_A1 | Up | 0.2638866091 |
| GSE28863_A2 | Up | 0.3974367104 |
| GSE28863_A3 | Down | -1.1181583977 |
| GSE28863_A4 | Up | 0.1311279169 |
| GSE48662 | Down | -0.1545615182 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022867 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050907 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
