HCSGD entry for NEIL3
1. General information
| Official gene symbol | NEIL3 |
|---|---|
| Entrez ID | 55247 |
| Gene full name | nei endonuclease VIII-like 3 (E. coli) |
| Other gene symbols | FGP2 FPG2 NEI3 hFPG2 hNEI3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000405 | Bubble DNA binding | ISS | molecular_function |
| GO:0003684 | Damaged DNA binding | IEA | molecular_function |
| GO:0003690 | Double-stranded DNA binding | ISS | molecular_function |
| GO:0003697 | Single-stranded DNA binding | IDA | molecular_function |
| GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity | IDA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006284 | Base-excision repair | ISS | biological_process |
| GO:0006289 | Nucleotide-excision repair | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0019104 | DNA N-glycosylase activity | IDA ISS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9894126705 | 0.0000495498 | 0.9999902473 | 0.0114692982 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5067700280 |
| GSE13712_SHEAR | Down | -0.1742462489 |
| GSE13712_STATIC | Up | 0.2890554605 |
| GSE19018 | Down | -0.1153236658 |
| GSE19899_A1 | Down | -0.4626805415 |
| GSE19899_A2 | Down | -4.8055412911 |
| PubMed_21979375_A1 | Down | -1.6679891882 |
| PubMed_21979375_A2 | Down | -3.9593800704 |
| GSE35957 | Down | -2.3948836605 |
| GSE36640 | Down | -4.4226352357 |
| GSE54402 | Down | -1.1435749299 |
| GSE9593 | Down | -1.1298174850 |
| GSE43922 | Down | -1.6378892893 |
| GSE24585 | Down | -0.0311789373 |
| GSE37065 | Down | -0.4555463032 |
| GSE28863_A1 | Down | -0.4365106238 |
| GSE28863_A2 | Up | 0.5141739370 |
| GSE28863_A3 | Down | -0.7751103918 |
| GSE28863_A4 | Up | 0.0636385059 |
| GSE48662 | Down | -0.8201169380 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024831 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026184 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
