HCSGD entry for STEAP3
1. General information
| Official gene symbol | STEAP3 |
|---|---|
| Entrez ID | 55240 |
| Gene full name | STEAP family member 3, metalloreductase |
| Other gene symbols | AHMIO2 STMP3 TSAP6 dudlin-2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000293 | Ferric-chelate reductase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005771 | Multivesicular body | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006879 | Cellular iron ion homeostasis | TAS | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0009306 | Protein secretion | IDA IMP | biological_process |
| GO:0010008 | Endosome membrane | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0033572 | Transferrin transport | TAS | biological_process |
| GO:0043065 | Positive regulation of apoptotic process | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0009941985 | 0.8766993617 | 0.0857977049 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.0310490552 |
| GSE13712_SHEAR | Up | 0.5960671330 |
| GSE13712_STATIC | Up | 0.9204734328 |
| GSE19018 | Down | -0.2546267601 |
| GSE19899_A1 | Up | 0.7723963261 |
| GSE19899_A2 | Up | 2.1877663640 |
| PubMed_21979375_A1 | Up | 1.3988076369 |
| PubMed_21979375_A2 | Up | 1.8901672841 |
| GSE35957 | Down | -0.5643519919 |
| GSE36640 | Up | 1.4329882014 |
| GSE54402 | Up | 0.8061062622 |
| GSE9593 | Up | 0.0715092395 |
| GSE43922 | Up | 0.3292733472 |
| GSE24585 | Down | -1.0246257331 |
| GSE37065 | Up | 0.3415706711 |
| GSE28863_A1 | Down | -0.0983338711 |
| GSE28863_A2 | Up | 0.4869722953 |
| GSE28863_A3 | Down | -0.0243900525 |
| GSE28863_A4 | Up | 0.0287296529 |
| GSE48662 | Up | 0.2554311309 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027494 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031486 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049382 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052160 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
