HCSGD entry for UBA6
1. General information
| Official gene symbol | UBA6 |
|---|---|
| Entrez ID | 55236 |
| Gene full name | ubiquitin-like modifier activating enzyme 6 |
| Other gene symbols | E1-L2 MOP-4 UBE1L2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006464 | Cellular protein modification process | IEA | biological_process |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | IMP | biological_process |
| GO:0008641 | Small protein activating enzyme activity | IEA | molecular_function |
| GO:0016567 | Protein ubiquitination | IEA IMP | biological_process |
| GO:0016874 | Ligase activity | IEA | molecular_function |
| GO:0019780 | FAT10 activating enzyme activity | IMP | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0221714069 | 0.3362553816 | 0.3564896762 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1772987016 |
| GSE13712_SHEAR | Up | 0.6234402595 |
| GSE13712_STATIC | Up | 0.6018347198 |
| GSE19018 | Up | 0.3415722700 |
| GSE19899_A1 | Up | 0.9449161862 |
| GSE19899_A2 | Up | 0.2742230457 |
| PubMed_21979375_A1 | Up | 0.7835109688 |
| PubMed_21979375_A2 | Up | 0.6413665050 |
| GSE35957 | Down | -0.1923557203 |
| GSE36640 | Down | -0.4685489871 |
| GSE54402 | Up | 0.6646258972 |
| GSE9593 | Down | -0.1461140688 |
| GSE43922 | Up | 0.7010326690 |
| GSE24585 | Down | -0.0164812834 |
| GSE37065 | Up | 0.2555907859 |
| GSE28863_A1 | Down | -0.5398184901 |
| GSE28863_A2 | Up | 0.1390747375 |
| GSE28863_A3 | Down | -1.1910962710 |
| GSE28863_A4 | Down | -0.2835901396 |
| GSE48662 | Down | -0.2275056038 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023853 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040121 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT045891 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-31-5p | MIMAT0000089 | MIRT049880 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052594 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
