HCSGD entry for PPP2R3A

1. General information

Official gene symbolPPP2R3A
Entrez ID5523
Gene full nameprotein phosphatase 2, regulatory subunit B'', alpha
Other gene symbolsPPP2R3 PR130 PR72
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000159Protein phosphatase type 2A complexIDA ISScellular_component
GO:0001754Eye photoreceptor cell differentiationIGIbiological_process
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0006470Protein dephosphorylationISSbiological_process
GO:0007525Somatic muscle developmentIGIbiological_process
GO:0008601Protein phosphatase type 2A regulator activityTASmolecular_function
GO:0045732Positive regulation of protein catabolic processIMPbiological_process
GO:0050790Regulation of catalytic activityTASbiological_process
GO:0061053Somite developmentISSbiological_process
GO:0090090Negative regulation of canonical Wnt signaling pathwayIGIbiological_process
GO:0090244Wnt signaling pathway involved in somitogenesisICbiological_process
GO:0090249Regulation of cell motility involved in somitogenic axis elongationIGIbiological_process
GO:0090263Positive regulation of canonical Wnt signaling pathwayIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.96714046580.00941878730.99999024730.1917979892

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3657346841
GSE13712_SHEARDown-0.9645865385
GSE13712_STATICDown-0.8556813638
GSE19018Up0.5697891059
GSE19899_A1Down-0.2102491813
GSE19899_A2Down-0.7287741883
PubMed_21979375_A1Down-0.8717592208
PubMed_21979375_A2Down-0.4599820752
GSE35957Down-0.0785564721
GSE36640Down-1.0315765972
GSE54402Down-0.3399704663
GSE9593Up0.0630814034
GSE43922Down-0.7243046993
GSE24585Up0.4105322079
GSE37065Up0.1697728583
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.2534600322

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-148b-3pMIMAT0000759MIRT019482MicroarrayFunctional MTI (Weak)17612493
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.