HCSGD entry for TMLHE


1. General information

Official gene symbolTMLHE
Entrez ID55217
Gene full nametrimethyllysine hydroxylase, epsilon
Other gene symbolsAUTSX6 BBOX2 TMLD TMLH TMLHED XAP130
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005506Iron ion bindingIEAmolecular_function
GO:0005739MitochondrionIDAcellular_component
GO:0005759Mitochondrial matrixTAScellular_component
GO:0016702Oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygenIEAmolecular_function
GO:0031418L-ascorbic acid bindingIEAmolecular_function
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045329Carnitine biosynthetic processIDA IEA TASbiological_process
GO:0050353Trimethyllysine dioxygenase activityIDA TASmolecular_function
GO:0051354Negative regulation of oxidoreductase activityIDAbiological_process
GO:0055114Oxidation-reduction processIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.87392286390.09846751640.99999024730.6000841630

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0947807270
GSE13712_SHEARDown-0.2879210921
GSE13712_STATICUp0.2378735188
GSE19018Up0.1267180139
GSE19899_A1Down-0.0466465267
GSE19899_A2Down-0.3325236011
PubMed_21979375_A1Up0.1023450750
PubMed_21979375_A2Down-0.0942264744
GSE35957Down-0.2266616908
GSE36640Down-0.1080769687
GSE54402Up0.0361437345
GSE9593Down-0.2432014805
GSE43922Down-0.4974296562
GSE24585Up0.2409289160
GSE37065Down-0.0635642907
GSE28863_A1Up0.5314545366
GSE28863_A2Down-0.1599467864
GSE28863_A3Down-0.7514786244
GSE28863_A4Down-0.0501134552
GSE48662Down-0.2265521590

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Vitamin CDB00126 NUTR00001 | APRD00084 | EXPT00568 | DB09541

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.