HCSGD entry for TMLHE
1. General information
| Official gene symbol | TMLHE |
|---|---|
| Entrez ID | 55217 |
| Gene full name | trimethyllysine hydroxylase, epsilon |
| Other gene symbols | AUTSX6 BBOX2 TMLD TMLH TMLHED XAP130 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005506 | Iron ion binding | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0016702 | Oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | IEA | molecular_function |
| GO:0031418 | L-ascorbic acid binding | IEA | molecular_function |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045329 | Carnitine biosynthetic process | IDA IEA TAS | biological_process |
| GO:0050353 | Trimethyllysine dioxygenase activity | IDA TAS | molecular_function |
| GO:0051354 | Negative regulation of oxidoreductase activity | IDA | biological_process |
| GO:0055114 | Oxidation-reduction process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8739228639 | 0.0984675164 | 0.9999902473 | 0.6000841630 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0947807270 |
| GSE13712_SHEAR | Down | -0.2879210921 |
| GSE13712_STATIC | Up | 0.2378735188 |
| GSE19018 | Up | 0.1267180139 |
| GSE19899_A1 | Down | -0.0466465267 |
| GSE19899_A2 | Down | -0.3325236011 |
| PubMed_21979375_A1 | Up | 0.1023450750 |
| PubMed_21979375_A2 | Down | -0.0942264744 |
| GSE35957 | Down | -0.2266616908 |
| GSE36640 | Down | -0.1080769687 |
| GSE54402 | Up | 0.0361437345 |
| GSE9593 | Down | -0.2432014805 |
| GSE43922 | Down | -0.4974296562 |
| GSE24585 | Up | 0.2409289160 |
| GSE37065 | Down | -0.0635642907 |
| GSE28863_A1 | Up | 0.5314545366 |
| GSE28863_A2 | Down | -0.1599467864 |
| GSE28863_A3 | Down | -0.7514786244 |
| GSE28863_A4 | Down | -0.0501134552 |
| GSE48662 | Down | -0.2265521590 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Vitamin C | DB00126 | NUTR00001 | APRD00084 | EXPT00568 | DB09541 |

