HCSGD entry for LEPREL1


1. General information

Official gene symbolLEPREL1
Entrez ID55214
Gene full nameleprecan-like 1
Other gene symbolsMCVD MLAT4 P3H2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005506Iron ion bindingIEAmolecular_function
GO:0005604Basement membraneIEA ISScellular_component
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005788Endoplasmic reticulum lumenTAScellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0008285Negative regulation of cell proliferationIDAbiological_process
GO:0016706Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donorsIEAmolecular_function
GO:0019511Peptidyl-proline hydroxylationIDAbiological_process
GO:0019797Procollagen-proline 3-dioxygenase activityIDAmolecular_function
GO:0030198Extracellular matrix organizationTASbiological_process
GO:0031418L-ascorbic acid bindingIEAmolecular_function
GO:0032963Collagen metabolic processIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.41736375520.01128868580.99999024730.2101340170

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0524753830
GSE13712_SHEARDown-0.1392137219
GSE13712_STATICUp0.1220008824
GSE19018Up0.5452821636
GSE19899_A1Down-2.2744456581
GSE19899_A2Down-0.3053495758
PubMed_21979375_A1Down-0.7061458276
PubMed_21979375_A2Down-2.5316990147
GSE35957Down-0.4497588786
GSE36640Up1.0969717119
GSE54402Down-0.4351785601
GSE9593Down-0.1835891327
GSE43922Down-1.0627082471
GSE24585Down-0.6051324013
GSE37065Up0.6516601225
GSE28863_A1Down-0.1129510916
GSE28863_A2Up0.0446286568
GSE28863_A3Up0.1056503310
GSE28863_A4Down-0.0095126297
GSE48662Up0.2049771187

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Vitamin CDB00126 NUTR00001 | APRD00084 | EXPT00568 | DB09541

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.