HCSGD entry for PLEKHG6

1. General information

Official gene symbolPLEKHG6
Entrez ID55200
Gene full namepleckstrin homology domain containing, family G (with RhoGef domain) member 6
Other gene symbolsMyoGEF
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000922Spindle poleIEAcellular_component
GO:0005089Rho guanyl-nucleotide exchange factor activityIEAmolecular_function
GO:0005096GTPase activator activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0032154Cleavage furrowIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.47478910760.79943470610.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0463004845
GSE13712_SHEARDown-0.0299021763
GSE13712_STATICUp0.0303943486
GSE19018Up0.1924969246
GSE19899_A1Down-0.0508593255
GSE19899_A2Up0.1525317547
PubMed_21979375_A1Up0.0397633057
PubMed_21979375_A2Up0.1461737520
GSE35957Down-0.2284446818
GSE36640Up0.2397468333
GSE54402Up0.0439994820
GSE9593Down-0.0949474073
GSE43922Up0.0283089392
GSE24585Up0.3062027653
GSE37065Up0.0461591075
GSE28863_A1Down-0.2503628559
GSE28863_A2Down-0.1324827933
GSE28863_A3Up0.3883457833
GSE28863_A4Up0.0836353601
GSE48662Down-0.0072939164

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.