HCSGD entry for AVPR1A

1. General information

Official gene symbol	AVPR1A
Entrez ID	552
Gene full name	arginine vasopressin receptor 1A
Other gene symbols	AVPR V1a AVPR1 V1aR
Links to Entrez Gene	Links to Entrez Gene

2. Neighbors in the network

This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID	GO term	Evidence	Category
GO:0001992	Regulation of systemic arterial blood pressure by vasopressin	IEA	biological_process
GO:0002125	Maternal aggressive behavior	IEA	biological_process
GO:0003084	Positive regulation of systemic arterial blood pressure	IEA	biological_process
GO:0005000	Vasopressin receptor activity	IEA	molecular_function
GO:0005080	Protein kinase C binding	TAS	molecular_function
GO:0005515	Protein binding	IPI	molecular_function
GO:0005768	Endosome	TAS	cellular_component
GO:0005886	Plasma membrane	TAS	cellular_component
GO:0005887	Integral component of plasma membrane	TAS	cellular_component
GO:0006091	Generation of precursor metabolites and energy	TAS	biological_process
GO:0007186	G-protein coupled receptor signaling pathway	TAS	biological_process
GO:0007202	Activation of phospholipase C activity	TAS	biological_process
GO:0007204	Positive regulation of cytosolic calcium ion concentration	IEA	biological_process
GO:0007621	Negative regulation of female receptivity	IEA	biological_process
GO:0007625	Grooming behavior	IEA	biological_process
GO:0008015	Blood circulation	TAS	biological_process
GO:0008284	Positive regulation of cell proliferation	IEA	biological_process
GO:0010460	Positive regulation of heart rate	IEA	biological_process
GO:0014049	Positive regulation of glutamate secretion	IEA	biological_process
GO:0014902	Myotube differentiation	IEA	biological_process
GO:0016021	Integral component of membrane	IEA	cellular_component
GO:0017046	Peptide hormone binding	IEA	molecular_function
GO:0019722	Calcium-mediated signaling	IEA	biological_process
GO:0021537	Telencephalon development	IEA	biological_process
GO:0030307	Positive regulation of cell growth	IEA	biological_process
GO:0031394	Positive regulation of prostaglandin biosynthetic process	IEA	biological_process
GO:0031410	Cytoplasmic vesicle	IEA	cellular_component
GO:0031894	V1A vasopressin receptor binding	IEA	molecular_function
GO:0032849	Positive regulation of cellular pH reduction	IEA	biological_process
GO:0035176	Social behavior	IEA	biological_process
GO:0035815	Positive regulation of renal sodium excretion	IEA	biological_process
GO:0042631	Cellular response to water deprivation	IEA	biological_process
GO:0042711	Maternal behavior	IEA	biological_process
GO:0042713	Sperm ejaculation	IEA	biological_process
GO:0043084	Penile erection	IEA	biological_process
GO:0045907	Positive regulation of vasoconstriction	IEA	biological_process
GO:0051412	Response to corticosterone	IEA	biological_process
GO:0051970	Negative regulation of transmission of nerve impulse	IEA	biological_process

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4. Expression levels in datasets

Meta-analysis result

p-value up	p-value down	FDR up	FDR down
0.3512698150	0.9441585578	0.9999902473	1.0000000000

Individual experiment result
( "-" represent NA in the specific microarray platform )

Data source	Up or down	Log fold change
GSE11954	Up	0.0195728045
GSE13712_SHEAR	Up	0.0903540438
GSE13712_STATIC	Up	0.0767057448
GSE19018	Up	0.0431624508
GSE19899_A1	Up	0.0717589104
GSE19899_A2	Down	-0.1162225734
PubMed_21979375_A1	Down	-0.0314635498
PubMed_21979375_A2	Down	-0.0093833918
GSE35957	Up	0.1192914609
GSE36640	Up	0.0400546575
GSE54402	Down	-0.0302651964
GSE9593	Up	0.0609661378
GSE43922	Up	0.0171412734
GSE24585	Up	1.0785995660
GSE37065	Down	-0.0034562709
GSE28863_A1	Up	0.0597389473
GSE28863_A2	Up	0.0920743480
GSE28863_A3	Up	0.1244760815
GSE28863_A4	Up	0.0895911122
GSE48662	Down	-0.0844456613

5. Regulation relationships with compounds/drugs/microRNAs

Compounds

Not regulated by compounds

Drugs

Name	Drug	Accession number
Desmopressin	DB00035	BTD00112 \| BTD00061 \| BIOD00112 \| BIOD00061
Vasopressin	DB00067	BTD00110 \| BIOD00110
Felypressin	DB00093	BTD00114 \| BIOD00114
Conivaptan	DB00872	APRD01302
Terlipressin	DB02638	EXPT03310
PH-284	DB05452	-
Tolvaptan	DB06212	-

MicroRNAs

mirTarBase

No target information from mirTarBase

mirRecord

No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.

Navigator

1.General information
2.Neighbors in the network
3.Gene Ontology Annotation
4.Expression levels
5.Regulation
6.Text-mining results

HCSGD entry for AVPR1A

1. General information

2. Neighbors in the network

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

4. Expression levels in datasets

Meta-analysis result

Individual experiment result ( "-" represent NA in the specific microarray platform )

( "-" represent NA in the specific microarray platform )

5. Regulation relationships with compounds/drugs/microRNAs

Compounds

Drugs

Name

Drug

Accession number

MicroRNAs

mirTarBase

mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.

Navigator

Individual experiment result
( "-" represent NA in the specific microarray platform )