HCSGD entry for SMG8
1. General information
| Official gene symbol | SMG8 |
|---|---|
| Entrez ID | 55181 |
| Gene full name | smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans) |
| Other gene symbols | C17orf71 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000184 | Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | IMP TAS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0016071 | MRNA metabolic process | TAS | biological_process |
| GO:0045859 | Regulation of protein kinase activity | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0022011322 | 0.9845768512 | 0.1264978166 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.7158395590 |
| GSE13712_SHEAR | Up | 0.6362876197 |
| GSE13712_STATIC | Up | 0.7515419403 |
| GSE19018 | Down | -0.3411061861 |
| GSE19899_A1 | Up | 0.5851786404 |
| GSE19899_A2 | Up | 1.0323975174 |
| PubMed_21979375_A1 | Up | 0.4431263347 |
| PubMed_21979375_A2 | Up | 1.3669116321 |
| GSE35957 | Down | -0.1538128405 |
| GSE36640 | Up | 0.8784537873 |
| GSE54402 | Up | 0.3530018898 |
| GSE9593 | Up | 0.1332069256 |
| GSE43922 | Up | 0.6564152738 |
| GSE24585 | Up | 0.3923953698 |
| GSE37065 | Up | 0.1391631521 |
| GSE28863_A1 | Up | 0.7709286287 |
| GSE28863_A2 | Up | 0.4353585934 |
| GSE28863_A3 | Down | -0.5019846753 |
| GSE28863_A4 | Down | -0.0180296140 |
| GSE48662 | Up | 0.0181091041 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
