HCSGD entry for ARHGEF10L
1. General information
| Official gene symbol | ARHGEF10L |
|---|---|
| Entrez ID | 55160 |
| Gene full name | Rho guanine nucleotide exchange factor (GEF) 10-like |
| Other gene symbols | GrinchGEF |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005089 | Rho guanyl-nucleotide exchange factor activity | IEA | molecular_function |
| GO:0005100 | Rho GTPase activator activity | IDA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0032320 | Positive regulation of Ras GTPase activity | IDA | biological_process |
| GO:0032321 | Positive regulation of Rho GTPase activity | IDA | biological_process |
| GO:0032933 | SREBP signaling pathway | IDA | biological_process |
| GO:0043085 | Positive regulation of catalytic activity | IDA | biological_process |
| GO:0043547 | Positive regulation of GTPase activity | IDA | biological_process |
| GO:0050790 | Regulation of catalytic activity | IDA | biological_process |
| GO:0051496 | Positive regulation of stress fiber assembly | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5133788458 | 0.6540807302 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0469563465 |
| GSE13712_SHEAR | Down | -0.2657670965 |
| GSE13712_STATIC | Down | -0.1513573212 |
| GSE19018 | Up | 0.0533897488 |
| GSE19899_A1 | Down | -0.0666922286 |
| GSE19899_A2 | Up | 0.1707495955 |
| PubMed_21979375_A1 | Down | -0.7751834564 |
| PubMed_21979375_A2 | Down | -0.1741672817 |
| GSE35957 | Up | 0.2775537745 |
| GSE36640 | Up | 0.2764735748 |
| GSE54402 | Up | 0.0153928706 |
| GSE9593 | Up | 0.2784302116 |
| GSE43922 | Up | 0.0531775863 |
| GSE24585 | Up | 0.0196278311 |
| GSE37065 | Up | 0.1486735487 |
| GSE28863_A1 | Up | 0.1301593088 |
| GSE28863_A2 | Up | 0.4181218872 |
| GSE28863_A3 | Down | -0.0111942649 |
| GSE28863_A4 | Down | -0.0771393816 |
| GSE48662 | Up | 0.0693163548 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-324-5p | MIMAT0000761 | MIRT043172 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
