HCSGD entry for RFWD3
1. General information
| Official gene symbol | RFWD3 |
|---|---|
| Entrez ID | 55159 |
| Gene full name | ring finger and WD repeat domain 3 |
| Other gene symbols | RNF201 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002039 | P53 binding | IPI | molecular_function |
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006281 | DNA repair | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0010212 | Response to ionizing radiation | IDA | biological_process |
| GO:0016567 | Protein ubiquitination | IDA | biological_process |
| GO:0016605 | PML body | IEA | cellular_component |
| GO:0031571 | Mitotic G1 DNA damage checkpoint | IMP | biological_process |
| GO:0097371 | MDM2/MDM4 family protein binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7693930284 | 0.0041263554 | 0.9999902473 | 0.1306977136 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1825936569 |
| GSE13712_SHEAR | Up | 0.5854154130 |
| GSE13712_STATIC | Up | 0.0778621241 |
| GSE19018 | Down | -0.8356713221 |
| GSE19899_A1 | Down | -0.6881065380 |
| GSE19899_A2 | Down | -1.4831925065 |
| PubMed_21979375_A1 | Down | -1.0701299688 |
| PubMed_21979375_A2 | Down | -1.3910615915 |
| GSE35957 | Down | -1.3978767603 |
| GSE36640 | Down | -2.0111578898 |
| GSE54402 | Up | 0.0613069044 |
| GSE9593 | Down | -0.6383706518 |
| GSE43922 | Down | -0.2357022565 |
| GSE24585 | Down | -0.1290806488 |
| GSE37065 | Down | -0.0556493435 |
| GSE28863_A1 | Up | 0.5457667104 |
| GSE28863_A2 | Up | 0.8712431005 |
| GSE28863_A3 | Down | -0.4155940844 |
| GSE28863_A4 | Up | 0.0798573871 |
| GSE48662 | Down | -0.1716454191 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-340-5p | MIMAT0004692 | MIRT019540 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022290 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024660 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026221 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-484 | MIMAT0002174 | MIRT041944 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-339-5p | MIMAT0000764 | MIRT042746 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT046102 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051730 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
