HCSGD entry for MTPAP
1. General information
| Official gene symbol | MTPAP |
|---|---|
| Entrez ID | 55149 |
| Gene full name | mitochondrial poly(A) polymerase |
| Other gene symbols | PAPD1 SPAX4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | IDA | molecular_function |
| GO:0002134 | UTP binding | IDA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0004652 | Polynucleotide adenylyltransferase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IDA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006378 | MRNA polyadenylation | IDA | biological_process |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0030145 | Manganese ion binding | IDA | molecular_function |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0042803 | Protein homodimerization activity | IPI | molecular_function |
| GO:0071044 | Histone mRNA catabolic process | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5640285437 | 0.4234080468 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2222604897 |
| GSE13712_SHEAR | Up | 0.2022628466 |
| GSE13712_STATIC | Up | 0.1380295001 |
| GSE19018 | Down | -0.3855850372 |
| GSE19899_A1 | Down | -0.0856552592 |
| GSE19899_A2 | Up | 0.2336882253 |
| PubMed_21979375_A1 | Up | 0.5592548843 |
| PubMed_21979375_A2 | Up | 0.7455480772 |
| GSE35957 | Down | -0.1463308227 |
| GSE36640 | Down | -0.7461402111 |
| GSE54402 | Up | 0.1696903241 |
| GSE9593 | Down | -0.2020141603 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Down | -0.0924244508 |
| GSE28863_A2 | Down | -0.0863644252 |
| GSE28863_A3 | Down | -0.0169859116 |
| GSE28863_A4 | Up | 0.0220680613 |
| GSE48662 | Down | -0.3242531723 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027699 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028117 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047923 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
