HCSGD entry for ELP3
1. General information
| Official gene symbol | ELP3 |
|---|---|
| Entrez ID | 55140 |
| Gene full name | elongator acetyltransferase complex subunit 3 |
| Other gene symbols | KAT9 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0004402 | Histone acetyltransferase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | IDA TAS | biological_process |
| GO:0006368 | Transcription elongation from RNA polymerase II promoter | IDA | biological_process |
| GO:0008023 | Transcription elongation factor complex | IDA | cellular_component |
| GO:0008080 | N-acetyltransferase activity | IEA | molecular_function |
| GO:0008607 | Phosphorylase kinase regulator activity | IDA | molecular_function |
| GO:0016591 | DNA-directed RNA polymerase II, holoenzyme | IDA | cellular_component |
| GO:0030335 | Positive regulation of cell migration | IEA ISS | biological_process |
| GO:0033588 | Elongator holoenzyme complex | IDA | cellular_component |
| GO:0042325 | Regulation of phosphorylation | IDA | biological_process |
| GO:0045859 | Regulation of protein kinase activity | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0050790 | Regulation of catalytic activity | IDA | biological_process |
| GO:0051536 | Iron-sulfur cluster binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3617607766 | 0.5374283880 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2097631675 |
| GSE13712_SHEAR | Up | 0.2455557004 |
| GSE13712_STATIC | Up | 0.0230139273 |
| GSE19018 | Down | -0.6843165063 |
| GSE19899_A1 | Down | -0.2700960940 |
| GSE19899_A2 | Up | 0.2749493609 |
| PubMed_21979375_A1 | Up | 0.5293617007 |
| PubMed_21979375_A2 | Up | 0.0389121003 |
| GSE35957 | Down | -0.2976069223 |
| GSE36640 | Down | -0.4332632934 |
| GSE54402 | Up | 0.0704744272 |
| GSE9593 | Up | 0.1160552343 |
| GSE43922 | Down | -0.0103631508 |
| GSE24585 | Up | 0.0823760824 |
| GSE37065 | Up | 0.0856406242 |
| GSE28863_A1 | Up | 0.3447329930 |
| GSE28863_A2 | Up | 0.6102401076 |
| GSE28863_A3 | Down | -0.1904796443 |
| GSE28863_A4 | Down | -0.0862411316 |
| GSE48662 | Down | -0.0536444353 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT031429 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-342-5p | MIMAT0004694 | MIRT038216 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041378 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
