HCSGD entry for PPP1R10
1. General information
| Official gene symbol | PPP1R10 |
|---|---|
| Entrez ID | 5514 |
| Gene full name | protein phosphatase 1, regulatory subunit 10 |
| Other gene symbols | CAT53 FB19 PNUTS PP1R10 R111 p99 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000785 | Chromatin | ISS | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0004864 | Protein phosphatase inhibitor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006606 | Protein import into nucleus | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0072357 | PTW/PP1 phosphatase complex | ISS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0298291250 | 0.7830531515 | 0.3999006619 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4943281967 |
| GSE13712_SHEAR | Up | 0.3784096669 |
| GSE13712_STATIC | Up | 0.3131264300 |
| GSE19018 | Down | -0.2420985252 |
| GSE19899_A1 | Up | 0.0420359451 |
| GSE19899_A2 | Up | 0.3968764204 |
| PubMed_21979375_A1 | Up | 1.0196004812 |
| PubMed_21979375_A2 | Up | 1.1321264005 |
| GSE35957 | Down | -0.7691384114 |
| GSE36640 | Up | 0.4817076455 |
| GSE54402 | Up | 0.6373353820 |
| GSE9593 | Up | 0.0125699103 |
| GSE43922 | Up | 0.1700916333 |
| GSE24585 | Up | 0.3551413936 |
| GSE37065 | Up | 0.0657452201 |
| GSE28863_A1 | Up | 0.3616186236 |
| GSE28863_A2 | Up | 0.6119950695 |
| GSE28863_A3 | Down | -0.3775165269 |
| GSE28863_A4 | Down | -0.3022428665 |
| GSE48662 | Down | -0.1438231560 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT007193 | Luciferase reporter assay | Functional MTI | 23426265 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT017879 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028486 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1914-3p | MIMAT0007890 | MIRT035778 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040376 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042999 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051563 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
