HCSGD entry for FANCL
1. General information
| Official gene symbol | FANCL |
|---|---|
| Entrez ID | 55120 |
| Gene full name | Fanconi anemia, complementation group L |
| Other gene symbols | FAAP43 PHF9 POG |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IDA IEA ISS TAS | molecular_function |
| GO:0005635 | Nuclear envelope | IEA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006281 | DNA repair | IEA IMP TAS | biological_process |
| GO:0006513 | Protein monoubiquitination | IDA | biological_process |
| GO:0006974 | Cellular response to DNA damage stimulus | IMP | biological_process |
| GO:0007276 | Gamete generation | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016874 | Ligase activity | IEA | molecular_function |
| GO:0031625 | Ubiquitin protein ligase binding | IPI | molecular_function |
| GO:0042127 | Regulation of cell proliferation | IEA | biological_process |
| GO:0043240 | Fanconi anaemia nuclear complex | IDA IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9616164545 | 0.0084668706 | 0.9999902473 | 0.1841600989 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0457809897 |
| GSE13712_SHEAR | Down | -0.1800181931 |
| GSE13712_STATIC | Up | 0.1192359113 |
| GSE19018 | Down | -0.2963375525 |
| GSE19899_A1 | Down | -0.7797415682 |
| GSE19899_A2 | Down | -0.6826565558 |
| PubMed_21979375_A1 | Up | 0.6646233136 |
| PubMed_21979375_A2 | Down | -1.5451740129 |
| GSE35957 | Down | -0.7188704559 |
| GSE36640 | Down | -0.7474657977 |
| GSE54402 | Up | 0.0696730619 |
| GSE9593 | Down | -0.7606932865 |
| GSE43922 | Down | -0.6667782771 |
| GSE24585 | Up | 0.3248725099 |
| GSE37065 | Up | 0.2895232127 |
| GSE28863_A1 | Down | -0.0608185034 |
| GSE28863_A2 | Down | -0.2058781759 |
| GSE28863_A3 | Down | -0.3458049889 |
| GSE28863_A4 | Down | -0.3045225698 |
| GSE48662 | Down | -0.3625457435 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
