HCSGD entry for MAGOHB
1. General information
| Official gene symbol | MAGOHB |
|---|---|
| Entrez ID | 55110 |
| Gene full name | mago-nashi homolog B (Drosophila) |
| Other gene symbols | MGN2 mago magoh |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0008380 | RNA splicing | IEA | biological_process |
| GO:0051028 | MRNA transport | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9877829452 | 0.0085983815 | 0.9999902473 | 0.1849068627 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0603445320 |
| GSE13712_SHEAR | Down | -0.0330942473 |
| GSE13712_STATIC | Up | 0.0547723355 |
| GSE19018 | Down | -0.3686568549 |
| GSE19899_A1 | Down | -0.2130838474 |
| GSE19899_A2 | Down | -1.0748536121 |
| PubMed_21979375_A1 | Down | -0.9407906113 |
| PubMed_21979375_A2 | Down | -0.8397010623 |
| GSE35957 | Down | -0.3490477473 |
| GSE36640 | Down | -0.9995321608 |
| GSE54402 | Down | -0.2918805480 |
| GSE9593 | Down | -0.2253349845 |
| GSE43922 | Down | -0.5393375445 |
| GSE24585 | Down | -0.5019822659 |
| GSE37065 | Down | -0.0985746713 |
| GSE28863_A1 | Up | 0.1441521035 |
| GSE28863_A2 | Up | 0.0274295609 |
| GSE28863_A3 | Down | -0.4322805585 |
| GSE28863_A4 | Up | 0.2062715092 |
| GSE48662 | Down | -0.2447227093 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050618 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 26206181 | We also performed functional studies by silencing nine of these genes in young cells, which demonstrated that RNA interference-mediated knockdown of LEPRE1, LIMA1/EPLIN, MAGOHA and MAGOHB induces a premature senescent phenotype in IMR90 cells |
| 26206181 | In conclusion, these results for the first time highlight a possible role of LEPRE1, LIMA1/EPLIN, MAGOHA and MAGOHB in the biology of cellular senescence/aging, thus contributing to gain a deeper knowledge of the molecular mechanisms involved in the senescence program |
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