HCSGD entry for AVP

1. General information

Official gene symbolAVP
Entrez ID551
Gene full namearginine vasopressin
Other gene symbolsADH ARVP AVP-NPII AVRP VP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002125Maternal aggressive behaviorIEAbiological_process
GO:0003084Positive regulation of systemic arterial blood pressureIEAbiological_process
GO:0004672Protein kinase activityIDAmolecular_function
GO:0004871Signal transducer activityIDAmolecular_function
GO:0005102Receptor bindingTASmolecular_function
GO:0005184Neuropeptide hormone activityTASmolecular_function
GO:0005185Neurohypophyseal hormone activityIEAmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006091Generation of precursor metabolites and energyTASbiological_process
GO:0006468Protein phosphorylationIDAbiological_process
GO:0006833Water transportTASbiological_process
GO:0007165Signal transductionIDAbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationIEAbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0007621Negative regulation of female receptivityIEAbiological_process
GO:0007625Grooming behaviorIEAbiological_process
GO:0007626Locomotory behaviorIEAbiological_process
GO:0008284Positive regulation of cell proliferationIEAbiological_process
GO:0010628Positive regulation of gene expressionIDAbiological_process
GO:0014049Positive regulation of glutamate secretionIEAbiological_process
GO:0030141Secretory granuleIEAcellular_component
GO:0030307Positive regulation of cell growthIEAbiological_process
GO:0030425DendriteIEAcellular_component
GO:0030819Positive regulation of cAMP biosynthetic processIEAbiological_process
GO:0031394Positive regulation of prostaglandin biosynthetic processIEAbiological_process
GO:0031894V1A vasopressin receptor bindingIPImolecular_function
GO:0031895V1B vasopressin receptor bindingIEAmolecular_function
GO:0032849Positive regulation of cellular pH reductionIEAbiological_process
GO:0033138Positive regulation of peptidyl-serine phosphorylationIDAbiological_process
GO:0033574Response to testosteroneIEAbiological_process
GO:0035094Response to nicotineIEAbiological_process
GO:0035176Social behaviorIEAbiological_process
GO:0035813Regulation of renal sodium excretionIEAbiological_process
GO:0042310VasoconstrictionIEAbiological_process
GO:0042538Hyperosmotic salinity responseIEAbiological_process
GO:0042711Maternal behaviorIEAbiological_process
GO:0043027Cysteine-type endopeptidase inhibitor activity involved in apoptotic processIDAmolecular_function
GO:0043066Negative regulation of apoptotic processIDAbiological_process
GO:0043084Penile erectionIEAbiological_process
GO:0043154Negative regulation of cysteine-type endopeptidase activity involved in apoptotic processIDAbiological_process
GO:0043252Sodium-independent organic anion transportTASbiological_process
GO:0045471Response to ethanolIEAbiological_process
GO:0045907Positive regulation of vasoconstrictionIEAbiological_process
GO:0050891Multicellular organismal water homeostasisIEAbiological_process
GO:0051970Negative regulation of transmission of nerve impulseIEAbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0070371ERK1 and ERK2 cascadeIDAbiological_process
GO:0070528Protein kinase C signalingIDAbiological_process
GO:0090201Negative regulation of release of cytochrome c from mitochondriaIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.60180408040.74786160860.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0319540695
GSE13712_SHEARDown-0.1247314704
GSE13712_STATICDown-0.0323662532
GSE19018Up0.2055862938
GSE19899_A1Down-0.2031496571
GSE19899_A2Down-0.0070563625
PubMed_21979375_A1Up0.0177401076
PubMed_21979375_A2Down-0.1637003437
GSE35957Up0.0832524625
GSE36640Down-0.0505820267
GSE54402Down-0.0274158306
GSE9593Up0.0122661414
GSE43922Up0.1317428100
GSE24585Down-0.0490272811
GSE37065Up0.0409732756
GSE28863_A1Down-0.1680811977
GSE28863_A2Up0.1376227239
GSE28863_A3Up0.3999035788
GSE28863_A4Down-0.0085582734
GSE48662Up0.2250704032

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018794MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

10739892Neuropeptide arginine-vasopressin((4-8)) (AVP(4-8)) is a metabolite of arginine-vasopressin which has been shown to have potent memory-enhancing activity, facilitate neurite elongation and prolongate cell aging
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