HCSGD entry for FKBP14
1. General information
| Official gene symbol | FKBP14 |
|---|---|
| Entrez ID | 55033 |
| Gene full name | FK506 binding protein 14, 22 kDa |
| Other gene symbols | EDSKMH FKBP22 IPBP12 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000413 | Protein peptidyl-prolyl isomerization | IBA | biological_process |
| GO:0003755 | Peptidyl-prolyl cis-trans isomerase activity | IBA IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005528 | FK506 binding | IBA | molecular_function |
| GO:0005788 | Endoplasmic reticulum lumen | TAS | cellular_component |
| GO:0006457 | Protein folding | IEA | biological_process |
| GO:0006987 | Activation of signaling protein activity involved in unfolded protein response | TAS | biological_process |
| GO:0016020 | Membrane | IBA | cellular_component |
| GO:0018208 | Peptidyl-proline modification | IBA | biological_process |
| GO:0030968 | Endoplasmic reticulum unfolded protein response | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0456754645 | 0.4467280422 | 0.4742737298 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1374106960 |
| GSE13712_SHEAR | Up | 0.2107677076 |
| GSE13712_STATIC | Up | 0.5385036092 |
| GSE19018 | Down | -0.7547111758 |
| GSE19899_A1 | Up | 0.1701507913 |
| GSE19899_A2 | Up | 0.1006383904 |
| PubMed_21979375_A1 | Up | 0.2000491952 |
| PubMed_21979375_A2 | Up | 0.7056487867 |
| GSE35957 | Up | 0.1793569507 |
| GSE36640 | Up | 1.0213971518 |
| GSE54402 | Down | -0.1049479602 |
| GSE9593 | Up | 0.4197104428 |
| GSE43922 | Up | 0.3286806733 |
| GSE24585 | Down | -0.2609447898 |
| GSE37065 | Down | -0.2043887072 |
| GSE28863_A1 | Up | 0.2530083630 |
| GSE28863_A2 | Up | 0.6338083395 |
| GSE28863_A3 | Down | -0.8186173862 |
| GSE28863_A4 | Down | -0.0959300780 |
| GSE48662 | Up | 0.1230859041 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018653 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT023029 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030076 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
