HCSGD entry for PHIP
1. General information
| Official gene symbol | PHIP |
|---|---|
| Entrez ID | 55023 |
| Gene full name | pleckstrin homology domain interacting protein |
| Other gene symbols | BRWD2 DCAF14 WDR11 ndrp |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001932 | Regulation of protein phosphorylation | ISS | biological_process |
| GO:0005158 | Insulin receptor binding | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005634 | Nucleus | ISS | cellular_component |
| GO:0006606 | Protein import into nucleus | IEA | biological_process |
| GO:0007010 | Cytoskeleton organization | IMP | biological_process |
| GO:0008284 | Positive regulation of cell proliferation | ISS | biological_process |
| GO:0008286 | Insulin receptor signaling pathway | NAS | biological_process |
| GO:0010800 | Positive regulation of peptidyl-threonine phosphorylation | IEA | biological_process |
| GO:0022604 | Regulation of cell morphogenesis | IMP | biological_process |
| GO:0033138 | Positive regulation of peptidyl-serine phosphorylation | IEA | biological_process |
| GO:0040008 | Regulation of growth | IEA | biological_process |
| GO:0043066 | Negative regulation of apoptotic process | ISS | biological_process |
| GO:0043568 | Positive regulation of insulin-like growth factor receptor signaling pathway | ISS | biological_process |
| GO:0045840 | Positive regulation of mitosis | ISS | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | ISS | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0070577 | Histone acetyl-lysine binding | IDA | molecular_function |
| GO:2001237 | Negative regulation of extrinsic apoptotic signaling pathway | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4423117777 | 0.5746641465 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0487024857 |
| GSE13712_SHEAR | Down | -0.0533314368 |
| GSE13712_STATIC | Down | -0.0287675098 |
| GSE19018 | Up | 0.2644075849 |
| GSE19899_A1 | Up | 0.2104803935 |
| GSE19899_A2 | Up | 0.0268336325 |
| PubMed_21979375_A1 | Up | 0.1901177131 |
| PubMed_21979375_A2 | Up | 0.1510671910 |
| GSE35957 | Down | -0.4433409305 |
| GSE36640 | Down | -0.1210187273 |
| GSE54402 | Up | 0.0392371644 |
| GSE9593 | Down | -0.3568246572 |
| GSE43922 | Down | -0.0209543896 |
| GSE24585 | Up | 0.2321102908 |
| GSE37065 | Up | 0.1829292484 |
| GSE28863_A1 | Up | 0.4936583373 |
| GSE28863_A2 | Up | 0.3712257437 |
| GSE28863_A3 | Down | -0.1584621306 |
| GSE28863_A4 | Down | -0.2755354790 |
| GSE48662 | Down | -0.2195194364 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-21-5p | MIMAT0000076 | MIRT030661 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031492 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-760 | MIMAT0004957 | MIRT036739 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
