HCSGD entry for MARCH1
1. General information
| Official gene symbol | MARCH1 |
|---|---|
| Entrez ID | 55016 |
| Gene full name | membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase |
| Other gene symbols | MARCH-I RNF171 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000209 | Protein polyubiquitination | IDA IEA | biological_process |
| GO:0002495 | Antigen processing and presentation of peptide antigen via MHC class II | IDA IEA | biological_process |
| GO:0004842 | Ubiquitin-protein ligase activity | IDA IEA | molecular_function |
| GO:0005764 | Lysosome | IDA | cellular_component |
| GO:0005765 | Lysosomal membrane | IEA ISS | cellular_component |
| GO:0005768 | Endosome | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA ISS | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006955 | Immune response | IDA IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030659 | Cytoplasmic vesicle membrane | IEA | cellular_component |
| GO:0031901 | Early endosome membrane | IDA IEA | cellular_component |
| GO:0031902 | Late endosome membrane | IDA IEA | cellular_component |
| GO:0032588 | Trans-Golgi network membrane | IEA ISS | cellular_component |
| GO:0042287 | MHC protein binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8438519015 | 0.3958415372 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0439547137 |
| GSE13712_SHEAR | Up | 0.1117892704 |
| GSE13712_STATIC | Up | 0.0198647675 |
| GSE19018 | Down | -0.0212948510 |
| GSE19899_A1 | Up | 0.2062590690 |
| GSE19899_A2 | Down | -0.0970591184 |
| PubMed_21979375_A1 | Down | -0.3640727716 |
| PubMed_21979375_A2 | Down | -0.2551508607 |
| GSE35957 | Up | 0.1476915335 |
| GSE36640 | Down | -0.4017742164 |
| GSE54402 | Down | -0.1809738052 |
| GSE9593 | Down | -0.0290803669 |
| GSE43922 | Up | 0.0123298334 |
| GSE24585 | Up | 0.2278124309 |
| GSE37065 | Up | 0.0215763038 |
| GSE28863_A1 | Down | -0.4947727741 |
| GSE28863_A2 | Down | -0.0299479792 |
| GSE28863_A3 | Up | 0.1558469595 |
| GSE28863_A4 | Up | 0.0426929352 |
| GSE48662 | Up | 0.0332183404 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018177 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029737 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
