HCSGD entry for TESC

1. General information

Official gene symbolTESC
Entrez ID54997
Gene full nametescalcin
Other gene symbolsCHP3 TSC
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000287Magnesium ion bindingISSmolecular_function
GO:0001726RuffleISScellular_component
GO:0004860Protein kinase inhibitor activityIEAmolecular_function
GO:0005509Calcium ion bindingIDA IEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA ISScellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0008285Negative regulation of cell proliferationIMPbiological_process
GO:0008584Male gonad developmentIEAbiological_process
GO:0010628Positive regulation of gene expressionIMPbiological_process
GO:0019212Phosphatase inhibitor activityISSmolecular_function
GO:0030027LamellipodiumIDAcellular_component
GO:0030219Megakaryocyte differentiationIEAbiological_process
GO:0030854Positive regulation of granulocyte differentiationIDAbiological_process
GO:0032417Positive regulation of sodium:hydrogen antiporter activityIDAbiological_process
GO:0032587Ruffle membraneIEAcellular_component
GO:0033628Regulation of cell adhesion mediated by integrinIMPbiological_process
GO:0042803Protein homodimerization activityISSmolecular_function
GO:0043086Negative regulation of catalytic activityISSbiological_process
GO:0045654Positive regulation of megakaryocyte differentiationIMPbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIMPbiological_process
GO:0050790Regulation of catalytic activityISSbiological_process
GO:0050821Protein stabilizationIDAbiological_process
GO:0051604Protein maturationIDAbiological_process
GO:0071300Cellular response to retinoic acidIDAbiological_process
GO:0072661Protein targeting to plasma membraneIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.37183988070.88712920480.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0927497298
GSE13712_SHEARUp0.0076906926
GSE13712_STATICDown-0.2139337635
GSE19018Up0.1121154766
GSE19899_A1Up0.2033512963
GSE19899_A2Up0.1939059829
PubMed_21979375_A1Up0.0796633603
PubMed_21979375_A2Up0.0132603726
GSE35957Down-0.0013805950
GSE36640Up0.2830264924
GSE54402Down-0.0175946204
GSE9593Up0.1537294195
GSE43922Up0.1588207024
GSE24585Down-0.1208499803
GSE37065Down-0.0952992954
GSE28863_A1Down-0.0273708554
GSE28863_A2Down-0.1666849416
GSE28863_A3Up0.4463581360
GSE28863_A4Up0.0281264577
GSE48662Down-0.0306206003

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.