HCSGD entry for PPM1G
1. General information
| Official gene symbol | PPM1G |
|---|---|
| Entrez ID | 5496 |
| Gene full name | protein phosphatase, Mg2+/Mn2+ dependent, 1G |
| Other gene symbols | PP2CG PP2CGAMMA PPP2CG |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004722 | Protein serine/threonine phosphatase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006470 | Protein dephosphorylation | TAS | biological_process |
| GO:0007050 | Cell cycle arrest | IEA | biological_process |
| GO:0035970 | Peptidyl-threonine dephosphorylation | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1245148703 | 0.3201011550 | 0.7202455085 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2132638071 |
| GSE13712_SHEAR | Up | 0.0838883925 |
| GSE13712_STATIC | Up | 0.1313646829 |
| GSE19018 | Down | -0.6601105058 |
| GSE19899_A1 | Up | 0.2054604790 |
| GSE19899_A2 | Up | 0.1122270780 |
| PubMed_21979375_A1 | Up | 0.5775640032 |
| PubMed_21979375_A2 | Up | 0.8864851352 |
| GSE35957 | Down | -1.1967742550 |
| GSE36640 | Down | -0.5808049249 |
| GSE54402 | Up | 0.7169657227 |
| GSE9593 | Down | -0.6837569065 |
| GSE43922 | Up | 0.4465251863 |
| GSE24585 | Down | -0.0718958777 |
| GSE37065 | Down | -0.1560754365 |
| GSE28863_A1 | Down | -0.0682623648 |
| GSE28863_A2 | Up | 0.1719012538 |
| GSE28863_A3 | Up | 0.2374636839 |
| GSE28863_A4 | Up | 0.0384829650 |
| GSE48662 | Down | -0.2514991388 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020613 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032202 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037135 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041984 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047658 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
