HCSGD entry for LPCAT2
1. General information
| Official gene symbol | LPCAT2 |
|---|---|
| Entrez ID | 54947 |
| Gene full name | lysophosphatidylcholine acyltransferase 2 |
| Other gene symbols | AYTL1 LysoPAFAT |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA ISS | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0005795 | Golgi stack | ISS | cellular_component |
| GO:0005811 | Lipid particle | IDA | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006663 | Platelet activating factor biosynthetic process | ISS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016746 | Transferase activity, transferring acyl groups | IEA | molecular_function |
| GO:0036151 | Phosphatidylcholine acyl-chain remodeling | IDA TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046474 | Glycerophospholipid biosynthetic process | TAS | biological_process |
| GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity | IDA ISS | molecular_function |
| GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity | ISS | molecular_function |
| GO:0061024 | Membrane organization | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0085261654 | 0.2271239163 | 0.2370178270 | 0.9166097209 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0484310542 |
| GSE13712_SHEAR | Down | -0.3537780165 |
| GSE13712_STATIC | Down | -0.5946428181 |
| GSE19018 | Up | 0.2881185226 |
| GSE19899_A1 | Up | 0.9205310368 |
| GSE19899_A2 | Up | 1.0362553491 |
| PubMed_21979375_A1 | Up | 1.2959399776 |
| PubMed_21979375_A2 | Up | 1.2468685455 |
| GSE35957 | Up | 0.2190458977 |
| GSE36640 | Up | 1.9507773996 |
| GSE54402 | Up | 0.2342832176 |
| GSE9593 | Up | 0.2802978664 |
| GSE43922 | Up | 0.6722588997 |
| GSE24585 | Up | 0.0298840552 |
| GSE37065 | Down | -0.2096017800 |
| GSE28863_A1 | Down | -0.7856225298 |
| GSE28863_A2 | Down | -0.3952501987 |
| GSE28863_A3 | Down | -0.9483105137 |
| GSE28863_A4 | Up | 0.2231302245 |
| GSE48662 | Up | 0.0524079074 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
